Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 8/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.43 |
| ▸ | PKLR | P30613 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7359991 | 0.86 | F2 (0.59) | F2ALDH1A1NTSR1PKLRMEN1 | |
| Hydrochloric Acid SCHEMBL7358299 | 0.83 | F2 (0.63) | F2ALDH1A1NTSR1PKLRMEN1 | |
| SCHEMBL7357627 | 0.83 | PKLR (0.46) | F2ALDH1A1NTSR1PKLRMEN1 | |
| Iodide SCHEMBL7361358 | 0.79 | F2 (0.57) | F2ALDH1A1NTSR1PKLRMEN1 | |
| SCHEMBL7353803 | 0.79 | PKLR (0.47) | F2ALDH1A1NTSR1PKLRMEN1 | |
| SCHEMBL7350234 | 0.79 | F2 (0.60) | F2ALDH1A1NTSR1PKLRMEN1 | |
| Hydrochloric Acid SCHEMBL6634654 | 0.77 | F2 (0.69) | F2ALDH1A1NTSR1PKLRMEN1 | |
| SCHEMBL7361534 | 0.76 | F2 (0.54) | F2ALDH1A1NTSR1PKLRMEN1 | |
| Hydrochloric Acid SCHEMBL7351752 | 0.75 | F2 (0.59) | F2ALDH1A1PKLRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8026588 | 0.74 | F2 (0.74) | F2ALDH1A1NTSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999028297-A1 | SUBSTITUTED INDOLES, HAVING A THROMBIN INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-06-10 | — | — | WO | disclosed |