Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKLR | P30613 | 5/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FABP1 | P07148 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7353803 | 0.92 | PKLR (0.47) | PKLRNTSR1F2ALDH1A1MEN1 | |
| SCHEMBL7352541 | 0.84 | PKLR (0.48) | PKLRNTSR1F2ALDH1A1MEN1 | |
| SCHEMBL7354601 | 0.83 | F2 (0.59) | PKLRNTSR1F2ALDH1A1MEN1 | |
| SCHEMBL7354443 | 0.80 | PKLR (0.47) | PKLRNTSR1F2ALDH1A1MEN1 | |
| SCHEMBL7352452 | 0.80 | ALDH1A1 (0.44) | PKLRALDH1A1MEN1KMT2AFABP1 | |
| SCHEMBL7358688 | 0.80 | PKLR (0.47) | PKLRNTSR1F2ALDH1A1MEN1 | |
| SCHEMBL6633872 | 0.76 | F2 (0.50) | PKLRNTSR1F2ALDH1A1MEN1 | |
| SCHEMBL8524454 | 0.75 | PKLR (0.49) | PKLRALDH1A1MEN1KMT2AFABP1 | |
| SCHEMBL7358689 | 0.75 | NTSR1 (0.67) | PKLRNTSR1ALDH1A1MEN1KMT2A | |
| SCHEMBL7357042 | 0.74 | MAPT (0.43) | ALDH1A1TP53GAALMNAHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999028297-A1 | SUBSTITUTED INDOLES, HAVING A THROMBIN INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-06-10 | — | — | WO | disclosed |