Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | LPL | P06858 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10374047 | 0.90 | ALDH1A1 (0.41) | GPR84CA2PLK1RAB9ANPC1 | |
| SCHEMBL5485288 | 0.86 | NPC1 (0.38) | MGLLRAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL29111860 | 0.83 | TAAR1 (0.39) | HTR2AMAPTGFERALDH1A1 | |
| SCHEMBL4551281 | 0.79 | FFAR1 (0.43) | CA2 | |
| SCHEMBL4551222 | 0.79 | MEN1 (0.44) | — | |
| SCHEMBL29111808 | 0.73 | LMNA (0.36) | CA2MAPTALDH1A1 | |
| SCHEMBL29111807 | 0.73 | LMNA (0.36) | CA2MAPTALDH1A1 | |
| SCHEMBL29111825 | 0.73 | LMNA (0.36) | CA2MAPTALDH1A1 | |
| SCHEMBL29265006 | 0.72 | NTRK1 (0.36) | — | |
| SCHEMBL29111858 | 0.69 | TAAR1 (0.39) | HTR2AMAPTGFERALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581939-B1 | N-SULPHONYL-2-OXOINDOLE DERIVATIVES HAVING AFFINITY FOR VASOPRESSIN AND/OR OCYTOCIN RECEPTORS | SANOFI SA (FR) | 1999-06-02 | — | — | EP | disclosed |
| EP-0581939-A1 | N-SULPHONYL-2-OXOINDOLE DERIVATIVES HAVING AFFINITY FOR VASOPRESSIN AND/OR OCYTOCIN RECEPTORS | SANOFI (FR) | 1994-02-09 | — | — | EP | disclosed |
| WO-1993015051-A1 | N-SULPHONYL-2-OXOINDOLE DERIVATIVES HAVING AFFINITY FOR VASOPRESSIN AND/OR OCYTOCIN RECEPTORS | ELF SANOFI (FR) | 1993-08-05 | — | — | WO | disclosed |