Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 2/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7356830 | 0.89 | HTR3A (0.58) | HTR3AADORA3MRGPRX4MAPTKMT2A | |
| SCHEMBL7354285 | 0.81 | HTR3A (0.55) | HTR3AMAPTKMT2AMEN1USP2 | |
| SCHEMBL25079149 | 0.80 | HTR3A (0.48) | HTR3AADORA3MAPTADORA2AADORA1 | |
| SCHEMBL30257342 | 0.80 | ADORA1 (0.56) | HTR3AADORA3MAPTADORA2AADORA1 | |
| SCHEMBL8877290 | 0.75 | HTR3A (0.47) | HTR3AADORA3MRGPRX4MAPTADORA2A | |
| SCHEMBL19340093 | 0.74 | PTGER1 (0.49) | ADORA3ADORA2AADORA1PTGER1SRD5A2 | |
| SCHEMBL7360572 | 0.73 | HTR3A (0.52) | HTR3AMAPTHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL8714077 | 0.72 | ELANE (0.50) | HTR3AADORA3KMT2AMEN1PTGER1 | |
| SCHEMBL31647374 | 0.72 | SSTR4 (0.46) | MAPTKMT2AMEN1TSHRPKM | |
| SCHEMBL31539866 | 0.72 | EDNRA (0.49) | HTR3AMRGPRX4MAPTPTGER1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991001316-A1 | NEW 9-AZABICYCLO[3.3.1]NONANE-DERIVATE | BEECHAM GROUP PLC (GB) | 1991-02-07 | — | — | WO | disclosed |