Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354904 | 0.89 | HTR3A (0.61) | HTR3AKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL25079149 | 0.77 | HTR3A (0.48) | HTR3AMAPTADORA2AMAOBADORA3 | |
| SCHEMBL30257342 | 0.77 | ADORA1 (0.56) | HTR3ASMN1; SMN2MAPTADORA2AADORA3 | |
| SCHEMBL8714077 | 0.74 | ELANE (0.50) | HTR3AKMT2AMEN1KDM4EADORA3 | |
| SCHEMBL20154228 | 0.73 | MAPT (0.57) | KMT2AMEN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL2835796 | 0.72 | POLB (0.57) | KMT2ALMNAALDH1A1L3MBTL1TSHR | |
| SCHEMBL8877290 | 0.72 | HTR3A (0.47) | HTR3AMAPTADORA2AKDM4EADORA3 | |
| SCHEMBL26179355 | 0.72 | KMT2A (0.55) | KMT2AMEN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL23505923 | 0.72 | KMT2A (0.55) | KMT2AMEN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL3926837 | 0.72 | TDP1 (0.58) | KMT2ALMNAALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991001316-A1 | NEW 9-AZABICYCLO[3.3.1]NONANE-DERIVATE | BEECHAM GROUP PLC (GB) | 1991-02-07 | — | — | WO | disclosed |