⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8350925 | 1.00 | — | — | |
| SCHEMBL8350928 | 1.00 | — | — | |
| SCHEMBL8346977 | 0.84 | — | — | |
| SCHEMBL8346975 | 0.84 | — | — | |
| SCHEMBL8717334 | 0.84 | POLB (0.31) | — | |
| SCHEMBL3971417 | 0.79 | KDM4E (0.46) | — | |
| SCHEMBL3118111 | 0.77 | L3MBTL1 (0.37) | — | |
| SCHEMBL460078 | 0.77 | L3MBTL1 (0.39) | — | |
| SCHEMBL3202848 | 0.76 | MTNR1A (0.48) | — | |
| SCHEMBL182827 | 0.74 | MAPT (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1110954-A1 | Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analgetics | Aventis Pharmaceuticals Inc. (US) | 2001-06-27 | — | — | EP | disclosed |
| EP-1052255-A1 | Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analgetics. | Aventis Pharmaceuticals Inc. (US) | 2000-11-15 | — | — | EP | disclosed |
| EP-0963984-A1 | Heteroarylpiperidines and piperazines and their use as antipsychotics and analgetics | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1999-12-15 | — | — | EP | disclosed |
| EP-0959076-A1 | Heteroarylperidines and piperazines and their use as antipsychotics and analgetics | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1999-11-24 | — | — | EP | disclosed |
| EP-0959075-A1 | Heteroarylpiperidines and piperazines and their use as antipsychotics and analgetics | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1999-11-24 | — | — | EP | disclosed |
| EP-0957102-A1 | Heteroarylpiperidines and piperazines and their use as antipsychotics and analgetics | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1999-11-17 | — | — | EP | disclosed |
| EP-0612318-A1 | HETEROARYLPIPERIDINES, PYRROLIDINES AND PIPERAZINES AND THEIR USE AS ANTIPSYCHOTICS AND ANALGETICS | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-08-31 | — | — | EP | disclosed |
| EP-0542136-A1 | Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analgetics | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-05-19 | — | — | EP | disclosed |
| WO-1993009102-A1 | HETEROARYLPIPERIDINES, PYRROLIDINES AND PIPERAZINES AND THEIR USE AS ANTIPSYCHOTICS AND ANALGETICS | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1993-05-13 | — | — | WO | disclosed |