Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 10/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | FKBP1A | P62942 | 7/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7355192 | 0.87 | ACE (0.57) | ACEGAAFKBP1AACE2 | |
| SCHEMBL7352944 | 0.86 | ACE (0.51) | ACEGAAFKBP1A | |
| SCHEMBL6439093 | 0.85 | ACE (0.62) | ACEFKBP1AACE2CTRB1 | |
| SCHEMBL4455535 | 0.82 | ELANE (0.58) | — | |
| SCHEMBL4455552 | 0.82 | ELANE (0.58) | — | |
| SCHEMBL7350737 | 0.82 | ELANE (0.58) | — | |
| SCHEMBL7426069 | 0.81 | ACE (0.59) | ACEFKBP1AACE2 | |
| SCHEMBL6436340 | 0.81 | ACE (0.59) | ACEFKBP1AACE2 | |
| SCHEMBL7148899 | 0.81 | ACE (0.63) | ACEFKBP1A | |
| SCHEMBL7537159 | 0.81 | ACE (0.63) | ACEFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993025574-A1 | INHIBITORS OF ANGIOTENSIN I CHYMASE(S) INCLUDING HUMAN HEART CHYMASE | PFIZER INC. (US) | 1993-12-23 | — | — | WO | disclosed |