Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.58 |
| ▸ | CTSG | P08311 | 1/20 | 0.58 |
| ▸ | CMA1 | P23946 | 13/20 | 0.52 |
| ▸ | XIAP | P98170 | 5/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7350737 | 1.00 | ELANE (0.58) | ELANECTSGCMA1XIAP | |
| SCHEMBL4455535 | 1.00 | ELANE (0.58) | ELANECTSGCMA1XIAP | |
| Hydrochloric Acid SCHEMBL6699938 | 0.91 | ELANE (0.66) | ELANECTSGCMA1 | |
| Hydrochloric Acid SCHEMBL7357221 | 0.91 | ELANE (0.66) | ELANECTSGCMA1 | |
| Hydrochloric Acid SCHEMBL6699949 | 0.91 | ELANE (0.66) | ELANECTSGCMA1 | |
| SCHEMBL7348515 | 0.88 | ELANE (0.57) | ELANECTSGCMA1XIAP | |
| SCHEMBL7348523 | 0.88 | ELANE (0.57) | ELANECTSGCMA1XIAP | |
| SCHEMBL7356337 | 0.88 | ELANE (0.57) | ELANECTSGCMA1XIAP | |
| SCHEMBL7355184 | 0.82 | ACE (0.57) | — | |
| SCHEMBL7349280 | 0.80 | CMA1 (0.66) | ELANECTSGCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054319-A1 | Methods and Compositions for the Treatment of Hypertension and Gastrointestinal Disorders | MICROBIA, INC. (US) | 2009-02-26 | — | — | US | disclosed |
| US-20040086537-A1 | Prophylactic or threapeutic composition for ocular circulation disorders | INOUE JUN (JP) | 2004-05-06 | — | — | US | disclosed |
| EP-1224945-A1 | TENSION-RELIEVING AGENTS FOR CILIARY MUSCLE | Senju Pharmaceutical Co., Ltd. (JP) | 2002-07-24 | — | — | EP | disclosed |
| EP-1112749-A2 | PREVENTIVES OR REMEDIES FOR EYE CIRCULATORY FAILURE | Senju Pharmaceutical Co., Ltd. (JP) | 2001-07-04 | — | — | EP | disclosed |
| WO-1993025574-A1 | INHIBITORS OF ANGIOTENSIN I CHYMASE(S) INCLUDING HUMAN HEART CHYMASE | PFIZER INC. (US) | 1993-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040086537-A1 | Prophylactic or threapeutic composition for ocular circulation disorders | CMA1, THOP1, TPSAB1 | ELANE 867/4885CTSG 31/4885CMA1 1/4885 |
| US-20090054319-A1 | Methods and Compositions for the Treatment of Hypertension and Gastrointestinal Disorders | PTGIS, PTGIR, GRPR | ELANE 2176/4885CTSG 1249/4885CMA1 313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.