Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 5/20 | 0.55 |
| ▸ | GRIK2 | Q13002 | 5/20 | 0.55 |
| ▸ | GRIK3 | Q13003 | 4/20 | 0.55 |
| ▸ | GRIK4 | Q16099 | 4/20 | 0.55 |
| ▸ | GRIK5 | Q16478 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.45 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.45 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.45 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7349770 | 0.94 | GRIK1 (0.61) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL7351187 | 0.91 | GRIK1 (0.55) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL9093775 | 0.85 | GRIA1 (0.58) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL7353360 | 0.85 | GRIK1 (0.59) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL7361295 | 0.83 | SIRT2 (0.46) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL7354618 | 0.82 | SIRT2 (0.46) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL9542780 | 0.82 | SIRT2 (0.52) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL8609548 | 0.81 | CYP1A2 (0.57) | MAPTSIRT2SIRT1GRIA1GRIA2 | |
| SCHEMBL7357748 | 0.80 | SIRT2 (0.48) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL7349783 | 0.79 | GRIA1 (0.45) | GRIK1GRIK2GRIK3GRIK4GRIK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057304-A | Quinoxaline-phosphonic acid derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |
| EP-0565683-A1 | QUINOXALINE DERIVATES WITH AFFINITY FOR QUISQUALATE-RECEPTORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-10-20 | — | — | EP | disclosed |
| WO-1993008173-A1 | QUINOXALINE DERIVATES WITH AFFINITY FOR QUISQUALATE-RECEPTORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-04-29 | — | — | WO | disclosed |