Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6226043 | 0.72 | ALDH1A1 (0.34) | MAPTGAAALOX5DAOTSHR | |
| SCHEMBL8330072 | 0.71 | MAPT (0.47) | MAPTGAAP2RX4ALOX5DAO | |
| SCHEMBL2568672 | 0.71 | GAA (0.35) | MAPTGAAP2RX4DAOTSHR | |
| SCHEMBL4703515 | 0.70 | MAPT (0.36) | MAPTGAAP2RX4ALOX5DAO | |
| Hydrochloric Acid SCHEMBL8332139 | 0.70 | MAPT (0.45) | MAPTGAAP2RX4ALOX5DAO | |
| SCHEMBL3519587 | 0.70 | GAA (0.31) | MAPTGAADAOTSHRNAPRT | |
| SCHEMBL27989619 | 0.69 | MAOA (0.42) | MAPTGAAALOX5MAOAMAOB | |
| SCHEMBL4044958 | 0.68 | MAPT (0.42) | MAPTGAAALOX5ALDH1A1MAOA | |
| SCHEMBL27246590 | 0.67 | MAPT (0.36) | MAPTGAAP2RX4TSHRSMN1; SMN2 | |
| SCHEMBL30857809 | 0.66 | MAOA (0.39) | MAPTGAAALOX5MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087937-A1 | CYCLIC HYDROXAMIC ACIDS AS METALLOPROTEINASE INHIBITORS | Du Pont Pharmaceuticals Company (US) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065867-A1 | CYCLIC HYDROXAMIC ACIDS AS METALLOPROTEINASE INHIBITORS | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-12-23 | — | — | WO | disclosed |