Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.39 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | ADH4 | P08319 | 1/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8100986 | 0.98 | ALDH1A1 (0.52) | TSHRALDH1A1POLBSMN1; SMN2L3MBTL1 | |
| Phosphoric Acid SCHEMBL506002 | 0.88 | S1PR2 (0.55) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| SCHEMBL22027474 | 0.87 | CNR1 (0.51) | CNR1CNR2 | |
| Phosphoric Acid SCHEMBL11447509 | 0.85 | S1PR2 (0.56) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| SCHEMBL17310374 | 0.85 | CYP2C19 (0.36) | TSHRALDH1A1POLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL1238087 | 0.82 | — | — | |
| SCHEMBL8871024 | 0.81 | TSHR (0.55) | TSHRALDH1A1POLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL4538493 | 0.81 | TSHR (0.55) | TSHRALDH1A1POLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL9575912 | 0.81 | TSHR (0.55) | TSHRALDH1A1POLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL3284743 | 0.81 | TSHR (0.55) | TSHRALDH1A1POLBSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9790246-B2 | Nickel compound and method of forming thin film using the nickel compound | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2017-10-17 | — | — | US | disclosed |
| US-20170198001-A1 | NICKEL COMPOUND AND METHOD OF FORMING THIN FILM USING THE NICKEL COMPOUND | ADEKA CORPORATION (JP) | 2017-07-13 | — | — | US | disclosed |
| US-9637511-B2 | Method of forming thin film using a heterostructured nickel compound | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2017-05-02 | — | — | US | disclosed |
| US-20150266913-A1 | NICKEL COMPOUND AND METHOD OF FORMING THIN FILM USING THE NICKEL COMPOUND | ADEKA CORPORATION (JP) | 2015-09-24 | — | — | US | disclosed |
| EP-0650476-B1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMA CO LTD (JP) | 2002-06-26 | — | — | EP | disclosed |
| US-6136826-A | AMINOPIPERIDINE COMPOUNDS SUBSTITUTED WITH ALKANOYL | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| US-5760058-A | Peripheral vasodilating agent containing piperidine derivative as active ingredient | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-02 | — | — | US | disclosed |
| US-5656642-A | Peripheral vasodilating agent containing piperidine derivative as active ingredient | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |
| US-5652247-A | VASOPRESSIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD (JP) | 1997-07-29 | — | — | US | disclosed |
| US-5436254-A | Vaopressin antagonists | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0382213-B1 | Biphenyl derivative, nerve cell degeneration repairing or protecting agent and process for preparing a phenyl derivative contained in the agent | OTSUKA PHARMA CO LTD (JP) | 1995-05-10 | — | — | EP | disclosed |
| WO-1994022826-A1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-13 | — | — | WO | disclosed |
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |
| US-5225402-A | Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |
| US-5053548-A | Containing hydroxy substituents; nervous system disorders | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1991-10-01 | — | — | US | disclosed |
| EP-0382213-A2 | Biphenyl derivative, nerve cell degeneration repairing or protecting agent and process for preparing a phenyl derivative contained in the agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150266913-A1 | NICKEL COMPOUND AND METHOD OF FORMING THIN FILM USING THE NICKEL COMPOUND | NIT2, NISCH, NOTCH4 | TSHR 4156/4885ALDH1A1 4485/4885POLB 4368/4885 |
| US-20170198001-A1 | NICKEL COMPOUND AND METHOD OF FORMING THIN FILM USING THE NICKEL COMPOUND | NIT2, NISCH, NOTCH4 | TSHR 4156/4885ALDH1A1 4485/4885POLB 4368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.