Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 6/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.55 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.55 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.55 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.55 |
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.49 |
| ▸ | FDPS | P14324 | 9/20 | 0.44 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL11447509 | 0.96 | S1PR2 (0.56) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL8100986 | 0.90 | ALDH1A1 (0.52) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL7355331 | 0.88 | TSHR (0.55) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| Phosphoric Acid SCHEMBL10874337 | 0.82 | S1PR2 (0.76) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| Phosphoric Acid SCHEMBL11024073 | 0.82 | S1PR2 (0.76) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| Phosphoric Acid SCHEMBL11503444 | 0.82 | S1PR2 (0.76) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| Phosphoric Acid SCHEMBL11503446 | 0.82 | S1PR2 (0.76) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| Phosphoric Acid SCHEMBL7115228 | 0.82 | S1PR2 (0.76) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| Phosphoric Acid SCHEMBL16774438 | 0.82 | S1PR2 (0.76) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| Phosphoric Acid SCHEMBL547511 | 0.82 | S1PR2 (0.76) | S1PR2S1PR1S1PR3S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11491091-B2 | Cooling product | SYMRISE AG (DE) | 2022-11-08 | — | — | US | disclosed |
| US-20190099342-A1 | COOLING PRODUCT | SYMRISE AG (DE) | 2019-04-04 | — | — | US | disclosed |
| EP-3434330-A1 | A METHOD FOR ENHANCING THE COOLING EFFECT OF A COOLING COMPOUND | Symrise AG (DE) | 2019-01-30 | — | — | EP | disclosed |
| US-9029415-B2 | Cooling mixtures with an enhanced cooling effect of 5-methyl-2-(propane-2-yl)cyclohexyl-N-ethyloxamate | SYMRISE AG (DE) | 2015-05-12 | — | — | US | disclosed |
| US-9005592-B2 | Compositions having HASE rheology modifiers | RHODIA OPERATIONS (FR) | 2015-04-14 | — | — | US | disclosed |
| US-20140099276-A1 | Compositions Having Hase Rheology Modifiers | RHODIA OPERATIONS (FR) | 2014-04-10 | — | — | US | disclosed |
| US-20130202543-A1 | USE OF POLYOLS FOR ENHANCING THE COOLING EFFECT OF A COOLING SUBSTANCE AND COOLING MIXTURES HAVING AN ENHANCED COOLING EFFECT | SYMRISE AG (DE) | 2013-08-08 | — | — | US | disclosed |
| EP-2579950-A2 | USE OF POLYOLS FOR ENHANCING THE COOLING EFFECT OF A COOLING SUBSTANCE AND COOLING MIXTURES HAVING AN ENHANCED COOLING EFFECT | Symrise AG (DE) | 2013-04-17 | — | — | EP | disclosed |
| US-20120029138-A1 | Anti-settling composition and methods for use | RHODIA OPERATIONS (US) | 2012-02-02 | — | — | US | disclosed |
| US-20110305657-A1 | Cooling Mixtures with an enhanced cooling effect of 5-methyl-2-(propane-2-yl)cyclohexyl-N-ethyloxamate | SYMRISE AG (DE) | 2011-12-15 | — | — | US | disclosed |
| US-20110280822-A1 | Structured surfactant system | SPECIALTY OPERATIONS FRANCE (FR) | 2011-11-17 | — | — | US | disclosed |
| US-20110256085-A1 | RHEOLOGY MODIFIER COMPOSITIONS AND METHODS OF USE | RHODIA OPERATIONS (FR) | 2011-10-20 | — | — | US | disclosed |
| US-20110223125-A1 | COMPOSITIONS WITH FREEZE THAW STABILITY | RHODIA OPERATIONS (FR) | 2011-09-15 | — | — | US | disclosed |
| WO-2011100660-A1 | COMPOSITIONS WITH FREEZE THAW STABILITY | RHODIA OPERATIONS (FR) | 2011-08-18 | — | — | WO | disclosed |
| WO-2010149798-A2 | USE OF POLYOLS FOR ENHANCING THE COOLING EFFECT OF A COOLING SUBSTANCE AND COOLING MIXTURES HAVING AN ENHANCED COOLING EFFECT | SYMRISE AG (DE) | 2010-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11491091-B2 | Cooling product | TRPA1, TRPV2, TRPV1 | S1PR2 1077/4885S1PR1 1708/4885S1PR3 1632/4885 |
| US-20190099342-A1 | COOLING PRODUCT | TRPA1, TRPV2, NISCH | S1PR2 1264/4885S1PR1 1762/4885S1PR3 1687/4885 |
| US-20110305657-A1 | Cooling Mixtures with an enhanced cooling effect of 5-methyl-2-(propane-2-yl)cyclohexyl-N-ethyloxamate | NT5C, SUCLG1, CUTA | S1PR2 1928/4885S1PR1 2521/4885S1PR3 1745/4885 |
| US-20110223125-A1 | COMPOSITIONS WITH FREEZE THAW STABILITY | C9, PUF60, BCL2L10 | S1PR2 500/4885S1PR1 499/4885S1PR3 427/4885 |
| US-20140099276-A1 | Compositions Having Hase Rheology Modifiers | WEE2, CCNE2, HPSE | S1PR2 813/4885S1PR1 1149/4885S1PR3 1142/4885 |
| US-20110280822-A1 | Structured surfactant system | TTR, SPAST, SMURF1 | S1PR2 271/4885S1PR1 177/4885S1PR3 34/4885 |
| US-20130202543-A1 | USE OF POLYOLS FOR ENHANCING THE COOLING EFFECT OF A COOLING SUBSTANCE AND COOLING MIXTURES HAVING AN ENHANCED COOLING EFFECT | CUTA, MCOLN2, MCOLN3 | S1PR2 534/4885S1PR1 575/4885S1PR3 337/4885 |
| US-20110256085-A1 | RHEOLOGY MODIFIER COMPOSITIONS AND METHODS OF USE | SFN, YWHAZ, DSG1 | S1PR2 542/4885S1PR1 338/4885S1PR3 213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.