Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.85 |
| ▸ | POLB | P06746 | 4/20 | 0.85 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.85 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.85 |
| ▸ | MEN1 | O00255 | 5/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.78 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.77 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.77 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.74 |
| ▸ | TP53 | P04637 | 2/20 | 0.74 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.74 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.74 |
| ▸ | FLT3 | P36888 | 4/20 | 0.71 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.70 |
| ▸ | GABRP | O00591 | 1/20 | 0.70 |
| ▸ | GABRD | O14764 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.70 |
| ▸ | PIM1 | P11309 | 1/20 | 0.70 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cirsimaritin SCHEMBL1663486 | 0.92 | POLB (1.00) | MAPTPOLBKDM4EADORA3MEN1 | |
| Cirsimaritin SCHEMBL29459674 | 0.92 | POLB (1.00) | MAPTPOLBKDM4EADORA3MEN1 | |
| SCHEMBL28040107 | 0.91 | POLB (1.00) | MAPTPOLBKDM4EADORA3MEN1 | |
| Tetramethylscutellarein SCHEMBL739115 | 0.88 | MEN1 (1.00) | MAPTPOLBKDM4EADORA3MEN1 | |
| SCHEMBL1764630 | 0.87 | CYP1A1 (1.00) | MAPTPOLBKDM4EADORA3MEN1 | |
| SCHEMBL30082755 | 0.87 | CYP1A1 (1.00) | MAPTPOLBKDM4EADORA3MEN1 | |
| SCHEMBL7127301 | 0.87 | CYP1A1 (0.86) | CYP1A1CYP1B1 | |
| SCHEMBL10031342 | 0.87 | CYP1A1 (0.81) | MAPTPOLBKDM4EMEN1KMT2A | |
| SCHEMBL737068 | 0.86 | MEN1 (0.78) | MAPTPOLBKDM4EADORA3MEN1 | |
| SCHEMBL17258307 | 0.86 | MEN1 (0.78) | MAPTPOLBKDM4EADORA3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119165087-A | Method for detecting multiple components in rhizoma coptidis green particles | 上海市第七人民医院(上海中医药大学附属第七人民医院) | 2024-12-20 | — | — | CN | claimed |
| CN-115315194-B | Hydroxy-and methoxy-substituted flavones and use thereof | 弗门尼舍有限公司 | 2024-06-21 | — | — | CN | claimed |
| US-20240114939-A1 | HYDROXY- AND METHOXY-SUBSTITUTED FLAVONES AND THEIR USE | FIRMENICH SA (CH) | 2024-04-11 | — | — | US | claimed |
| CN-115315194-A | Hydroxy-and methoxy-substituted flavones and their use | 弗门尼舍有限公司 | 2022-11-08 | — | — | CN | claimed |
| CN-119165087-A | Method for detecting multiple components in rhizoma coptidis green particles | 上海市第七人民医院(上海中医药大学附属第七人民医院) | 2024-12-20 | — | — | CN | disclosed |
| CN-115315194-B | Hydroxy-and methoxy-substituted flavones and use thereof | 弗门尼舍有限公司 | 2024-06-21 | — | — | CN | disclosed |
| US-20240114939-A1 | HYDROXY- AND METHOXY-SUBSTITUTED FLAVONES AND THEIR USE | FIRMENICH SA (CH) | 2024-04-11 | — | — | US | disclosed |
| EP-4258899-A1 | HYDROXY- AND METHOXY-SUBSTITUTED FLAVONES AND THEIR USE | Firmenich SA (CH) | 2023-10-18 | — | — | EP | disclosed |
| CN-115315194-A | Hydroxy-and methoxy-substituted flavones and their use | 弗门尼舍有限公司 | 2022-11-08 | — | — | CN | disclosed |
| WO-2022189155-A1 | HYDROXY- AND METHOXY-SUBSTITUTED FLAVONES AND THEIR USE | FIRMENICH SA (CH) | 2022-09-15 | — | — | WO | disclosed |
| CN-111116535-A | Pseudo-osbeckia chinensis flower extract and application thereof | 海南师范大学 | 2020-05-08 | — | — | CN | disclosed |
| US-8138165-B2 | Chromones and chromone derivatives and uses thereof | JENKEN BIOSCIENCES, INC. (US) | 2012-03-20 | — | — | US | disclosed |
| EP-1556031-A4 | CHROMONES AND CHROMONE DERIVATIVES AND USES THEREOF | JENKEN BIOSCIENCES INC (US) | 2009-03-25 | — | — | EP | disclosed |
| US-20060142211-A1 | Chromones and chromone derivatives and uses thereof | TAIWANJ PHARMACEUTICALS CO., LTD. (TW) | 2006-06-29 | — | — | US | disclosed |
| EP-1556031-A2 | CHROMONES AND CHROMONE DERIVATIVES AND USES THEREOF | Jenken Bioscience, Inc. (US) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004037193-A2 | CHROMONES AND CHROMONE DERIVATIVES AND USES THEREOF | JENKEN BIOSCIENCES, INC. (US) | 2004-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142211-A1 | Chromones and chromone derivatives and uses thereof | PROC, HMGB1, PYCARD | MAPT 3414/4885POLB 4669/4885KDM4E 3352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.