Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 4/20 | 1.00 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 1.00 |
| ▸ | AURKA | O14965 | 1/20 | 0.86 |
| ▸ | KDR | P35968 | 1/20 | 0.86 |
| ▸ | FLT3 | P36888 | 1/20 | 0.86 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.86 |
| ▸ | MEN1 | O00255 | 2/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.79 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.79 |
| ▸ | TP53 | P04637 | 1/20 | 0.79 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.79 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.73 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.73 |
| ▸ | KDM1A | O60341 | 1/20 | 0.73 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.73 |
| ▸ | XDH | P47989 | 1/20 | 0.73 |
| ▸ | IPMK | Q8NFU5 | 1/20 | 0.73 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.73 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30082755 | 1.00 | CYP1A1 (1.00) | CYP1A1CYP1B1AURKAKDRFLT3 | |
| SCHEMBL8062995 | 0.94 | CYP1A1 (0.88) | CYP1A1CYP1B1AURKAKDRFLT3 | |
| Eupatorin SCHEMBL30334912 | 0.93 | CYP1A1 (1.00) | CYP1A1CYP1B1AURKAKDRFLT3 | |
| Eupatorin SCHEMBL555597 | 0.93 | CYP1A1 (1.00) | CYP1A1CYP1B1AURKAKDRFLT3 | |
| Eupatorin SCHEMBL29386042 | 0.93 | CYP1A1 (1.00) | CYP1A1CYP1B1AURKAKDRFLT3 | |
| SCHEMBL7127301 | 0.92 | CYP1A1 (0.86) | CYP1A1CYP1B1 | |
| SCHEMBL10031342 | 0.90 | CYP1A1 (0.81) | CYP1A1CYP1B1AURKAKDRFLT3 | |
| Sinensetin SCHEMBL621101 | 0.88 | ABCB1 (1.00) | CYP1A1CYP1B1AURKAKDRFLT3 | |
| Sinensetin SCHEMBL29549544 | 0.88 | ABCB1 (1.00) | CYP1A1CYP1B1AURKAKDRFLT3 | |
| Sinensetin SCHEMBL29700880 | 0.88 | ABCB1 (1.00) | CYP1A1CYP1B1AURKAKDRFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240114939-A1 | HYDROXY- AND METHOXY-SUBSTITUTED FLAVONES AND THEIR USE | FIRMENICH SA (CH) | 2024-04-11 | — | — | US | claimed |
| EP-3703724-A1 | EXTRACT OF ORTHOSIPHON STAMINEUS, FORMULATIONS, AND USES THEREOF | NatureCeuticals Sdn. Bhd. (MY) | 2020-09-09 | — | — | EP | claimed |
| US-20140039044-A1 | Hydroxylated Polymethoxyflavone Compositions | WLLGEN, INC. (US) | 2014-02-06 | — | — | US | claimed |
| EP-2010194-A2 | HYDROXYLATED POLYMETHOXYFLAVONE COMPOSITIONS | Rutgers, The State University of New Jersey (US) | 2009-01-07 | — | — | EP | claimed |
| US-20070275106-A1 | Hydroxylated polymethoxyflavone compositions | WELLGEN, INC. | 2007-11-29 | — | — | US | claimed |
| WO-2007109071-A2 | HYDROXYLATED POLYMETHOXYFLAVONE COMPOSITIONS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2007-09-27 | — | — | WO | claimed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | claimed |
| JP-2003504327-A | — | — | 2003-02-04 | — | — | JP | claimed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | claimed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | claimed |
| EP-4251708-B1 | METHOD FOR PRODUCING A HIGH-PHENOLIC-CONTENT BIOOIL | THE UNIV OF NEW BRUNSWICK (CA) | 2026-02-11 | — | — | EP | disclosed |
| US-20240114939-A1 | HYDROXY- AND METHOXY-SUBSTITUTED FLAVONES AND THEIR USE | FIRMENICH SA (CH) | 2024-04-11 | — | — | US | disclosed |
| US-20230365764-A1 | METHOD FOR PRODUCING A HIGH-PHENOLIC-CONTENT BIOOIL | THE UNIVERSITY OF NEW BRUNSWICK (CA) | 2023-11-16 | — | — | US | disclosed |
| CN-113621622-B | Citrus polymethoxy flavone biosynthesis gene and application thereof | 华中农业大学 | 2023-10-27 | — | — | CN | disclosed |
| EP-4258899-A1 | HYDROXY- AND METHOXY-SUBSTITUTED FLAVONES AND THEIR USE | Firmenich SA (CH) | 2023-10-18 | — | — | EP | disclosed |
| WO-2003040077-A1 | COMBRETASTATIN A-4 DERIVATIVES HAVING ANTINEOPLASTIC ACTIVITY | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2003-05-15 | — | — | WO | disclosed |
| US-6555523-B1 | Such as 3',4'-diacetoxy-5,6,7-trimethoxyflavone or naringin in the treatment HIV, picornavirus, and/or respiratory virus | CASCADE ESTATES LTD. (MU) | 2003-04-29 | — | — | US | disclosed |
| US-6506792-B1 | Breast and endometrial cancers are major causes of death in Western women. In particular, tumours in endocrine-dependent tissues, such as the breast and endometrium, occur most frequently in postmenopausal women at a time when the ovaries | STERIX LIMITED (GB) | 2003-01-14 | — | — | US | disclosed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275106-A1 | Hydroxylated polymethoxyflavone compositions | PLIN5, FANCF, COXFA4 | CYP1A1 175/4885CYP1B1 264/4885AURKA 3715/4885 |
| US-20140039044-A1 | Hydroxylated Polymethoxyflavone Compositions | PLIN5, FANCF, COXFA4 | CYP1A1 175/4885CYP1B1 264/4885AURKA 3715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.