Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3292261 | 0.86 | TSHR (0.47) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL735598 | 0.80 | TSHR (0.46) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL735791 | 0.79 | TSHR (0.53) | TSHRHPGDALDH1A1ATMTHRB | |
| SCHEMBL10769504 | 0.79 | TSHR (0.64) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL5681395 | 0.77 | TSHR (1.00) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL11582291 | 0.77 | TSHR (1.00) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL15037 | 0.77 | — | — | |
| SCHEMBL1331857 | 0.77 | — | — | |
| SCHEMBL1330627 | 0.77 | — | — | |
| SCHEMBL1160870 | 0.75 | TSHR (0.96) | TSHRHPGDALDH1A1CYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8709543-B2 | Hydroxyl-terminated thiocarbonate containing compounds, polymers, and copolymers, and polyurethanes and urethane acrylics made therefrom | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2014-04-29 | — | — | US | claimed |
| EP-1773905-B1 | HYDROXYL-TERMINATED THIOCARBONATE CONTAINING COMPOUNDS, POLYMERS, AND COPOLYMERS, AND POLYURETHANES AND URETHANE ACRYLICS MADE THEREFROM | LUBRIZOL ADVANCED MAT INC (US) | 2013-10-09 | — | — | EP | claimed |
| US-8492576-B2 | Hydroxyl-terminated thiocarbonate containing compounds, polymers, and copolymers, and polyurethanes and urethane acrylics made therefrom | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2013-07-23 | — | — | US | claimed |
| US-20120171914-A1 | Hydroxyl-Terminated Thiocarbonate Containing Compounds, Polymers, and Copolymers, and Polyurethanes and Urethane Acrylics Made Therefrom | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2012-07-05 | — | — | US | claimed |
| EP-2272884-A2 | Hydroxyl-terminated thiocarbonate containing compounds, polymers, and copolymers, and polyurethanes and urethane acrylics made therefrom | Lubrizol Advanced Materials, Inc. (US) | 2011-01-12 | — | — | EP | claimed |
| EP-2272885-A2 | Hydroxyl-terminated thiocarbonate containing compounds, polymers, and copolymers, and polyurethanes and urethane acrylics made therefrom | Lubrizol Advanced Materials, Inc. (US) | 2011-01-12 | — | — | EP | claimed |
| EP-2270061-A2 | Hydroxyl-terminated thiocarbonate containing compounds, polymers, and copolymers, and polyurethanes and urethane acrylics made therefrom | Lubrizol Advanced Materials, Inc. (US) | 2011-01-05 | — | — | EP | claimed |
| US-20090312496-A1 | Hydroxyl-Terminated Thiocarbonate Containing Compounds, Polymers, and Copolymers, and Polyurethanes and Urethane Acrylics Made Therefrom | LAI JOHN TA-YUAN | 2009-12-17 | — | — | US | claimed |
| US-20080050995-A1 | Hydroxyl-Terminated Thiocarbonate Containing Compounds, Polymers, and Copolymers, and Polyurethanes and Urethane Acrylics Made Therefrom | LUBRIZOL ADVANCED MATERIALS, INC. | 2008-02-28 | — | — | US | claimed |
| EP-1786848-A1 | POLYURETHANES AND URETHANE ACRYLICS MADE FROM HYDROXYL-TERMINATED THIOCARBONATE CONTAINING COMPOUNDS | Noveon, Inc. (US) | 2007-05-23 | — | — | EP | claimed |
| EP-1773905-A1 | HYDROXYL-TERMINATED THIOCARBONATE CONTAINING COMPOUNDS, POLYMERS, AND COPOLYMERS, AND POLYURETHANES AND URETHANE ACRYLICS MADE THEREFROM | Noveon, Inc. (US) | 2007-04-18 | — | — | EP | claimed |
| WO-2006020116-A1 | HYDROXYL-TERMINATED THIOCARBONATE CONTAINING COMPOUNDS, POLYMERS, AND COPOLYMERS, AND POLYURETHANES AND URETHANE ACRYLICS MADE THEREFROM | NOVEON, INC. (US) | 2006-02-23 | — | — | WO | claimed |
| WO-2006020281-A1 | POLYURETHANES AND URETHANE ACRYLICS MADE FROM HYDROXYL-TERMINATED THIOCARBONATE CONTAINING COMPOUNDS | NOVEON, INC. (US) | 2006-02-23 | — | — | WO | claimed |
| US-20050009999-A1 | Hydroxyl-terminated thiocarbonate containing compounds, polymers, and copolymers, and polyurethanes and urethane acrylics made therefrom | LUBRIZOL ADVANCED MATERIALS, INC. | 2005-01-13 | — | — | US | claimed |
| US-8709543-B2 | Hydroxyl-terminated thiocarbonate containing compounds, polymers, and copolymers, and polyurethanes and urethane acrylics made therefrom | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2014-04-29 | — | — | US | disclosed |
| EP-1773905-B1 | HYDROXYL-TERMINATED THIOCARBONATE CONTAINING COMPOUNDS, POLYMERS, AND COPOLYMERS, AND POLYURETHANES AND URETHANE ACRYLICS MADE THEREFROM | LUBRIZOL ADVANCED MAT INC (US) | 2013-10-09 | — | — | EP | disclosed |
| US-8492576-B2 | Hydroxyl-terminated thiocarbonate containing compounds, polymers, and copolymers, and polyurethanes and urethane acrylics made therefrom | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2013-07-23 | — | — | US | disclosed |
| WO-2006020116-A1 | HYDROXYL-TERMINATED THIOCARBONATE CONTAINING COMPOUNDS, POLYMERS, AND COPOLYMERS, AND POLYURETHANES AND URETHANE ACRYLICS MADE THEREFROM | NOVEON, INC. (US) | 2006-02-23 | — | — | WO | disclosed |
| US-20050009999-A1 | Hydroxyl-terminated thiocarbonate containing compounds, polymers, and copolymers, and polyurethanes and urethane acrylics made therefrom | LUBRIZOL ADVANCED MATERIALS, INC. | 2005-01-13 | — | — | US | disclosed |
| US-6291620-B1 | Polymer synthesis | E. I. DU PONT DE NEMOURS AND COMPANY | 2001-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120171914-A1 | Hydroxyl-Terminated Thiocarbonate Containing Compounds, Polymers, and Copolymers, and Polyurethanes and Urethane Acrylics Made Therefrom | ALKBH3, HAAO, BHMT2 | TSHR 3660/4885HPGD 129/4885ALDH1A1 931/4885 |
| US-20090312496-A1 | Hydroxyl-Terminated Thiocarbonate Containing Compounds, Polymers, and Copolymers, and Polyurethanes and Urethane Acrylics Made Therefrom | ALKBH3, BHMT2, ALKBH2 | TSHR 2857/4885HPGD 223/4885ALDH1A1 190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.