Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.89 |
| ▸ | CTSL | P07711 | 7/20 | 0.61 |
| ▸ | CTSB | P07858 | 7/20 | 0.61 |
| ▸ | CTSH | P09668 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7295283 | 0.95 | CTSK (0.85) | CTSKCTSLCTSBCTSH | |
| SCHEMBL7349225 | 0.85 | CTSK (0.77) | CTSKCTSLCTSBCTSHSMN1; SMN2 | |
| SCHEMBL19050936 | 0.84 | CTSK (0.72) | CTSKCTSLCTSBCTSH | |
| SCHEMBL7296186 | 0.83 | CTSK (0.72) | CTSKCTSLCTSBCTSH | |
| SCHEMBL7374446 | 0.83 | CTSK (0.72) | CTSKCTSLCTSBCTSH | |
| SCHEMBL5674735 | 0.83 | CTSK (0.77) | CTSKCTSLCTSBCTSH | |
| SCHEMBL5674738 | 0.83 | CTSK (0.77) | CTSKCTSLCTSBCTSH | |
| SCHEMBL7294615 | 0.81 | CTSK (0.60) | CTSKCTSLNPC1LMNARAB9A | |
| SCHEMBL7286884 | 0.80 | CTSK (0.76) | CTSKCTSLCTSBCTSHNPC1 | |
| SCHEMBL3719520 | 0.79 | CTSK (0.63) | CTSKCTSLNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652247-A | VASOPRESSIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD (JP) | 1997-07-29 | — | — | US | disclosed |
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |
| US-5225402-A | Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |