Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 14/20 | 0.72 |
| ▸ | CTSB | P07858 | 10/20 | 0.62 |
| ▸ | CTSL | P07711 | 7/20 | 0.62 |
| ▸ | CTSH | P09668 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7374446 | 1.00 | CTSK (0.72) | CTSKCTSBCTSLCTSH | |
| SCHEMBL9069670 | 0.91 | CTSK (0.61) | CTSKCTSBCTSLCTSH | |
| SCHEMBL3131036 | 0.87 | CTSK (0.57) | CTSKCTSBCTSLCTSH | |
| SCHEMBL7288757 | 0.86 | CTSK (0.57) | CTSKCTSBCTSLCTSH | |
| SCHEMBL9083440 | 0.86 | CTSK (0.57) | CTSKCTSBCTSLCTSH | |
| SCHEMBL7413026 | 0.86 | CTSK (0.57) | CTSKCTSBCTSLCTSH | |
| SCHEMBL7356148 | 0.83 | CTSK (0.89) | CTSKCTSBCTSLCTSH | |
| SCHEMBL630290 | 0.82 | CTSB (0.66) | CTSBCTSL | |
| SCHEMBL3337955 | 0.82 | CTSB (0.66) | CTSBCTSL | |
| SCHEMBL3132344 | 0.82 | CTSB (0.66) | CTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107761-A2 | 4-QUINOLINEMETHANOL DERIVATIVES AS PURINE RECEPTOR ANTAGONISTS (II) | VERNALIS RESEARCH LIMITED (GB) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000013682-A2 | 4-QUINOLINEMETHANOL DERIVATIVES AS PURINE RECEPTOR ANTAGONISTS.(II) | VERNALIS RESEARCH LIMITED (GB) | 2000-03-16 | — | — | WO | disclosed |
| WO-1993012076-A1 | REAGENTS FOR AUTOMATED SYNTHESIS OF PEPTIDE ANALOGS | CORVAS INTERNATIONAL INC. (US) | 1993-06-24 | — | — | WO | disclosed |
| EP-0376012-A2 | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |
| EP-0342541-A2 | Retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1989-11-23 | — | — | EP | disclosed |