Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7328227 | 0.79 | IDH1 (0.34) | HTR3ATSHR | |
| SCHEMBL3485175 | 0.69 | DRD3 (0.42) | HRH3DRD2CHRM2CHRM3CHRM4 | |
| SCHEMBL4234192 | 0.69 | HRH3 (0.44) | HRH3 | |
| Hydrochloric Acid SCHEMBL4152474 | 0.69 | DRD3 (0.41) | HRH3DRD2CHRM2CHRM3CHRM4 | |
| SCHEMBL15976741 | 0.68 | CHRM2 (0.39) | HRH3LTA4HPTGS2DRD2CHRM2 | |
| SCHEMBL4234289 | 0.68 | MEN1 (0.32) | — | |
| SCHEMBL9640284 | 0.68 | CHRM2 (0.46) | CHRM2CHRM3CHRM4CHRM1HTR3A | |
| SCHEMBL4538423 | 0.67 | — | — | |
| SCHEMBL5790059 | 0.65 | ALDH1A1 (0.40) | TSHR | |
| SCHEMBL20069146 | 0.65 | DRD2 (0.56) | LTA4HPTGS2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4921860-A | Quinuclidyl- and tropanyl-pyridyl ethers as 5-HT3 receptor antagonists | JOHN WYETH AND BROTHER, LIMITED (GB) | 1990-05-01 | — | — | US | disclosed |