Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.41 |
| ▸ | TUBB | P07437 | 3/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7356228 | 0.85 | TUBB4A (0.42) | LMNASMN1; SMN2TUBB4ATUBBTUBA3C | |
| SCHEMBL5686671 | 0.81 | CYP3A4 (0.44) | LMNASMN1; SMN2TUBB4ATUBBTUBA3C | |
| SCHEMBL7356380 | 0.78 | IDH1 (0.50) | ALOX5CYP3A4HPGDHSD17B10CALM1 | |
| SCHEMBL7352238 | 0.77 | CYP3A4 (0.36) | HTR6CYP3A4CA2KCNA3 | |
| SCHEMBL7349242 | 0.76 | ALDH1A1 (0.53) | LMNASMN1; SMN2ALOX5KDM4EALDH1A1 | |
| SCHEMBL30644004 | 0.75 | TNKS2 (0.53) | LMNASMN1; SMN2TUBB4ATUBBTUBA3C | |
| SCHEMBL7940582 | 0.75 | PPARG (0.45) | LMNASMN1; SMN2TUBB4ATUBBTUBA3C | |
| SCHEMBL27456264 | 0.73 | TUBB4A (0.59) | LTA4HTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL20679778 | 0.72 | KDM4E (0.65) | LTA4HTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL806505 | 0.72 | ALDH1A1 (0.47) | HTR6LMNASMN1; SMN2TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0834508-B1 | Substituted biphenyl or phenylpyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-08-16 | — | — | EP | disclosed |
| US-5877190-A | PHOSPHODIESTERASE INHIBITOR | ADIR ET COMPAGNIE (FR) | 1999-03-02 | — | — | US | disclosed |
| EP-0834508-A1 | Substituted biphenyl or phenylpyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-04-08 | — | — | EP | disclosed |