Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.57 |
| ▸ | CTSG | P08311 | 1/20 | 0.57 |
| ▸ | CMA1 | P23946 | 16/20 | 0.52 |
| ▸ | XIAP | P98170 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348515 | 1.00 | ELANE (0.57) | ELANECTSGCMA1XIAP | |
| SCHEMBL7348523 | 1.00 | ELANE (0.57) | ELANECTSGCMA1XIAP | |
| SCHEMBL4455552 | 0.88 | ELANE (0.58) | ELANECTSGCMA1XIAP | |
| SCHEMBL4455535 | 0.88 | ELANE (0.58) | ELANECTSGCMA1XIAP | |
| SCHEMBL7350737 | 0.88 | ELANE (0.58) | ELANECTSGCMA1XIAP | |
| SCHEMBL7348394 | 0.88 | ELANE (0.46) | ELANECTSGCMA1XIAP | |
| SCHEMBL7348938 | 0.88 | CAPN1 (0.57) | XIAP | |
| SCHEMBL7348952 | 0.88 | CAPN1 (0.57) | XIAP | |
| SCHEMBL7347204 | 0.87 | OPRM1 (0.49) | XIAP | |
| SCHEMBL7355087 | 0.86 | ACE (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993025574-A1 | INHIBITORS OF ANGIOTENSIN I CHYMASE(S) INCLUDING HUMAN HEART CHYMASE | PFIZER INC. (US) | 1993-12-23 | — | — | WO | disclosed |