Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359372 | 0.93 | F10 (0.49) | F10KCNH2 | |
| SCHEMBL7372750 | 0.84 | KCNMA1 (0.46) | F10SMN1; SMN2NPC1ALDH1A1TSHR | |
| SCHEMBL6712441 | 0.77 | NPC1 (0.46) | F10SMN1; SMN2NPC1TSHRRAB9A | |
| SCHEMBL7359881 | 0.76 | F10 (0.42) | F10SMN1; SMN2NPC1ALDH1A1PKM | |
| SCHEMBL7356464 | 0.76 | F10 (0.43) | F10SMN1; SMN2NPC1ALDH1A1PKM | |
| SCHEMBL6106785 | 0.76 | F10 (0.52) | F10SMN1; SMN2NPC1ALDH1A1PKM | |
| SCHEMBL6107083 | 0.75 | F10 (0.47) | F10SMN1; SMN2NPC1ALDH1A1RAB9A | |
| Trifluoroacetic Acid SCHEMBL6108073 | 0.75 | F10 (0.56) | F10SMN1; SMN2NPC1ALDH1A1PKM | |
| SCHEMBL7356229 | 0.75 | F10 (0.48) | F10KCNH2 | |
| SCHEMBL3152348 | 0.75 | F10 (0.51) | F10KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140903-A1 | AROMATIC AMIDES | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039118-A1 | AROMATIC AMIDES | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |