Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.38 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359372 | 0.90 | F10 (0.49) | F10 | |
| SCHEMBL7381197 | 0.85 | KCNMA1 (0.52) | KCNMA1KDM4EGAAHPGDALOX15 | |
| SCHEMBL7356466 | 0.84 | F10 (0.47) | TSHRF10SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL7372751 | 0.75 | KCNMA1 (0.46) | KCNMA1KDM4EGAAHPGDALOX15 | |
| SCHEMBL5758058 | 0.75 | KCNMA1 (0.55) | KCNMA1KDM4EGAAHPGDALOX15 | |
| SCHEMBL8266905 | 0.74 | IRAK4 (0.49) | KCNMA1KDM4EGAAHPGDALOX15 | |
| Hydrochloric Acid SCHEMBL3166356 | 0.73 | IRAK4 (0.49) | KCNMA1KDM4EGAAHPGDALOX15 | |
| SCHEMBL7358439 | 0.72 | F10 (0.51) | KDM4EF10ALDH1A1NPC1RAB9A | |
| SCHEMBL6107083 | 0.72 | F10 (0.47) | ALOX15F10SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL5758733 | 0.72 | KDM4E (0.48) | KCNMA1KDM4EGAAHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140881-A1 | ANTITHROMBOTIC AMIDES | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039111-A1 | ANTITHROMBOTIC AMIDES | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |