Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.50 |
| ▸ | VNN1 | O95497 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371103 | 0.95 | HTT (0.53) | HTTF2RL1VNN1SMN1; SMN2CTBP2 | |
| SCHEMBL6936332 | 0.88 | HTT (0.56) | HTTF2RL1VNN1SMN1; SMN2CTBP2 | |
| SCHEMBL4641839 | 0.86 | HTT (0.50) | HTTF2RL1SMN1; SMN2CTBP2ALDH1A1 | |
| SCHEMBL9234996 | 0.84 | CNR1 (0.54) | HTTF2RL1CYP3A4CYP2C19 | |
| SCHEMBL10743710 | 0.83 | HTT (0.54) | HTTF2RL1VNN1SMN1; SMN2CTBP2 | |
| SCHEMBL3006056 | 0.81 | HTT (0.59) | HTTF2RL1SMN1; SMN2CTBP2ALDH1A1 | |
| SCHEMBL20610767 | 0.81 | F2RL1 (0.68) | F2RL1SMN1; SMN2ALDH1A1ALOX5POLB | |
| SCHEMBL4641825 | 0.81 | HTT (0.51) | HTTF2RL1SMN1; SMN2CTBP2ALDH1A1 | |
| SCHEMBL3628705 | 0.80 | HTT (0.68) | HTTF2RL1SMN1; SMN2CTBP2ALDH1A1 | |
| SCHEMBL8636964 | 0.80 | HTT (0.58) | HTTF2RL1VNN1SMN1; SMN2CTBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1589153-A | Prevention or treatment of urinary disorders | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2005-03-02 | — | — | CN | disclosed |
| EP-1140934-A1 | BENZISOXAZOLES AND PHENONES AS $g(a) 2?-ANTAGONISTS | Janssen Pharmaceutica N.V. (BE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037466-A1 | BENZISOXAZOLES AND PHENONES AS α2-ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2000-06-29 | — | — | WO | disclosed |