Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.39 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.39 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7355830 | 0.78 | ALDH1A1 (0.46) | KDM4EGAAMAPTALDH1A1PRSS1 | |
| Hydrochloric Acid SCHEMBL7350935 | 0.78 | ALDH1A1 (0.42) | KDM4EGAAMAPTALDH1A1TDP1 | |
| SCHEMBL7362067 | 0.78 | F2 (0.49) | KDM4EGAAMAPTALDH1A1PRSS1 | |
| Hydrochloric Acid SCHEMBL7350491 | 0.77 | ALDH1A1 (0.45) | KDM4EGAAMAPTALDH1A1PRSS1 | |
| Iodide SCHEMBL7355199 | 0.76 | ALDH1A1 (0.42) | KDM4EMAPTALDH1A1TDP1PRSS1 | |
| Hydrochloric Acid SCHEMBL7354330 | 0.76 | ALDH1A1 (0.44) | KDM4EALDH1A1PRSS1F2ITGB3 | |
| SCHEMBL7424087 | 0.76 | ALDH1A1 (0.47) | KDM4EGAAMAPTALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL7358442 | 0.75 | ALDH1A1 (0.45) | KDM4EGAAMAPTALDH1A1PRSS1 | |
| Iodide SCHEMBL7351413 | 0.74 | F2 (0.40) | KDM4EGAAMAPTALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL7356265 | 0.74 | ALDH1A1 (0.40) | KDM4EMAPTALDH1A1TDP1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999028297-A1 | SUBSTITUTED INDOLES, HAVING A THROMBIN INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-06-10 | — | — | WO | disclosed |