Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.49 |
| ▸ | F10 | P00742 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357066 | 0.78 | KDM4E (0.42) | F2F10MAPTALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL7355830 | 0.78 | ALDH1A1 (0.46) | F2F10MAPTALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL7354952 | 0.77 | PLAU (0.40) | F2F10MAPTLMNAPLAU | |
| Hydrochloric Acid SCHEMBL7358442 | 0.77 | ALDH1A1 (0.45) | F2F10MAPTALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL7350491 | 0.77 | ALDH1A1 (0.45) | F2F10MAPTALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL7350339 | 0.76 | SIRT1 (0.41) | F2F10MAPTALDH1A1MITF | |
| Hydrochloric Acid SCHEMBL7362315 | 0.76 | F2 (0.39) | F2F10MAPTALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL7350935 | 0.76 | ALDH1A1 (0.42) | F2F10MAPTALDH1A1KDM4E | |
| Iodide SCHEMBL7355199 | 0.76 | ALDH1A1 (0.42) | F2F10MAPTALDH1A1KDM4E | |
| SCHEMBL7360233 | 0.76 | KEAP1 (0.38) | F2F10MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999028297-A1 | SUBSTITUTED INDOLES, HAVING A THROMBIN INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-06-10 | — | — | WO | disclosed |