Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | APEX1 | P27695 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | WNT3A | P56704 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30977784 | 0.82 | KMT2A (0.75) | KMT2AALDH1A1MEN1TDP1POLB | |
| SCHEMBL7348772 | 0.81 | ALDH1A1 (0.55) | KMT2AALDH1A1MEN1TDP1POLB | |
| SCHEMBL15354269 | 0.79 | ALDH1A1 (1.00) | KMT2AALDH1A1MEN1TDP1POLB | |
| SCHEMBL7587416 | 0.77 | MEN1 (0.67) | KMT2AALDH1A1MEN1TDP1POLB | |
| SCHEMBL9903771 | 0.76 | MAPT (0.48) | KMT2AALDH1A1MEN1TDP1POLB | |
| SCHEMBL28492769 | 0.76 | CTNNB1 (0.69) | KMT2AALDH1A1MEN1TDP1POLB | |
| SCHEMBL7376695 | 0.75 | KMT2A (0.47) | KMT2AALDH1A1MEN1TDP1POLB | |
| SCHEMBL7351464 | 0.75 | F2 (0.52) | KMT2AALDH1A1MEN1TDP1POLB | |
| SCHEMBL29029980 | 0.73 | KMT2A (0.85) | KMT2AALDH1A1MEN1TDP1POLB | |
| SCHEMBL10371814 | 0.73 | ALDH1A1 (0.47) | KMT2AALDH1A1MEN1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0834508-B1 | Substituted biphenyl or phenylpyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-08-16 | — | — | EP | disclosed |
| US-5877190-A | PHOSPHODIESTERASE INHIBITOR | ADIR ET COMPAGNIE (FR) | 1999-03-02 | — | — | US | disclosed |
| EP-0834508-A1 | Substituted biphenyl or phenylpyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-04-08 | — | — | EP | disclosed |