Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357261 | 0.81 | KMT2A (0.64) | ALDH1A1KMT2APOLBMEN1THRB | |
| SCHEMBL19438782 | 0.80 | PTGS2 (0.53) | ALDH1A1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL7376695 | 0.79 | KMT2A (0.47) | ALDH1A1KMT2APOLBMEN1THRB | |
| SCHEMBL28182937 | 0.79 | ACVR1 (0.51) | ALDH1A1KMT2APOLBMEN1THRB | |
| SCHEMBL5076584 | 0.79 | SMN1; SMN2 (0.65) | ALDH1A1KMT2APOLBMEN1THRB | |
| SCHEMBL15354269 | 0.74 | ALDH1A1 (1.00) | ALDH1A1KMT2APOLBMEN1THRB | |
| SCHEMBL28183747 | 0.71 | CTNNB1 (0.40) | ALDH1A1KMT2APOLBMEN1RAB9A | |
| SCHEMBL28492769 | 0.71 | CTNNB1 (0.69) | ALDH1A1KMT2APOLBMEN1THRB | |
| SCHEMBL13142806 | 0.70 | KMT2A (0.62) | ALDH1A1KMT2APOLBMEN1THRB | |
| SCHEMBL28183749 | 0.70 | CTNNB1 (0.40) | ALDH1A1KMT2APOLBMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0834508-B1 | Substituted biphenyl or phenylpyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-08-16 | — | — | EP | disclosed |
| US-5877190-A | PHOSPHODIESTERASE INHIBITOR | ADIR ET COMPAGNIE (FR) | 1999-03-02 | — | — | US | disclosed |
| EP-0834508-A1 | Substituted biphenyl or phenylpyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-04-08 | — | — | EP | disclosed |