Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 10/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7356229 | 0.94 | F10 (0.48) | F10MEN1KMT2ARECQLKCNH2 | |
| SCHEMBL6107051 | 0.92 | F10 (0.47) | F10MEN1KMT2ARECQLKCNH2 | |
| SCHEMBL6714678 | 0.84 | NPC1 (0.53) | F10RAB9ANPC1SMN1; SMN2ALOX15 | |
| Hydrochloric Acid SCHEMBL7356962 | 0.84 | F10 (0.47) | F10 | |
| Hydrochloric Acid SCHEMBL7358233 | 0.84 | F10 (0.49) | F10KCNH2 | |
| SCHEMBL6108227 | 0.82 | CHEK1 (0.50) | F10MEN1KMT2ARECQLKCNH2 | |
| Hydrochloric Acid SCHEMBL7446146 | 0.82 | F10 (0.49) | F10MEN1KMT2AKCNH2RAB9A | |
| Hydrochloric Acid SCHEMBL6108557 | 0.80 | F10 (0.59) | F10MEN1KMT2ARECQLKCNH2 | |
| SCHEMBL7360451 | 0.80 | AKT1 (0.47) | F10MEN1KMT2ARECQLKCNH2 | |
| SCHEMBL7358439 | 0.79 | F10 (0.51) | F10KCNH2RAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140903-A1 | AROMATIC AMIDES | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039118-A1 | AROMATIC AMIDES | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |