Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7381197 | 0.86 | KCNMA1 (0.52) | F10ALDH1A1RAB9ANPC1KDM4E | |
| Hydrochloric Acid SCHEMBL7358233 | 0.85 | F10 (0.49) | F10KCNH2KLKB1 | |
| SCHEMBL6714678 | 0.85 | NPC1 (0.53) | F10RAB9ANPC1 | |
| SCHEMBL7356229 | 0.84 | F10 (0.48) | F10KCNH2KLKB1 | |
| Hydrochloric Acid SCHEMBL7446146 | 0.82 | F10 (0.49) | F10ALDH1A1RAB9ANPC1KCNH2 | |
| SCHEMBL6107653 | 0.81 | F10 (0.52) | F10POLBALDH1A1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL7356962 | 0.79 | F10 (0.47) | F10KLKB1 | |
| SCHEMBL7357775 | 0.79 | F10 (0.45) | F10RAB9ANPC1KDM4EKCNH2 | |
| SCHEMBL7359372 | 0.79 | F10 (0.49) | F10KCNH2KLKB1 | |
| SCHEMBL7365101 | 0.78 | F10 (0.46) | F10RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140903-A1 | AROMATIC AMIDES | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039118-A1 | AROMATIC AMIDES | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |