Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.47 |
| ▸ | F10 | P00742 | 14/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6413590 | 0.87 | AKT1 (0.45) | AKT1F10 | |
| SCHEMBL7356229 | 0.86 | F10 (0.48) | F10KCNH2F2MEN1RECQL | |
| SCHEMBL6415440 | 0.86 | F10 (0.49) | AKT1F10MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6712997 | 0.84 | F10 (0.48) | AKT1F10 | |
| SCHEMBL6107051 | 0.81 | F10 (0.47) | F10KCNH2MEN1RECQLKMT2A | |
| Hydrochloric Acid SCHEMBL7455665 | 0.81 | AKT1 (0.47) | AKT1F10 | |
| SCHEMBL7357775 | 0.80 | F10 (0.45) | F10KCNH2MEN1RECQLKMT2A | |
| SCHEMBL7366704 | 0.80 | ALDH1A1 (0.48) | F10MEN1KMT2A | |
| SCHEMBL7447691 | 0.80 | AKT1 (0.46) | AKT1F10 | |
| SCHEMBL6107299 | 0.79 | F10 (0.51) | F10KCNH2F2KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140903-A1 | AROMATIC AMIDES | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039118-A1 | AROMATIC AMIDES | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |