Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Isophthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.55 |
| ▸ | PPARG | P37231 | 7/20 | 0.55 |
| ▸ | PPARD | Q03181 | 7/20 | 0.55 |
| ▸ | PPARA | Q07869 | 7/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TLR2 | O60603 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | FABP4 | P15090 | 2/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.55 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isophthalic Acid SCHEMBL4952753 | 0.93 | HDAC3 (0.53) | LTB4RPPARAHDAC11KMT2AHSD17B10 | |
| Isophthalic Acid SCHEMBL11324134 | 0.91 | KMT2A (0.58) | TSHRKMT2ACES2CES1 | |
| Isophthalic Acid SCHEMBL6666925 | 0.91 | HDAC3 (0.59) | PPARAHDAC11TDP1HSD17B10 | |
| Isophthalic Acid SCHEMBL10976494 | 0.91 | HDAC3 (0.59) | PPARAHDAC11TDP1HSD17B10 | |
| Isophthalic Acid SCHEMBL123533 | 0.91 | HDAC3 (0.59) | PPARAHDAC11TDP1HSD17B10 | |
| Isophthalic Acid SCHEMBL5951008 | 0.89 | FFAR4 (0.51) | AKR1B1LTB4RGPR84PPARGPPARD | |
| Benzoic Acid SCHEMBL10947409 | 0.89 | CES2 (0.62) | AKR1B1GPR84PPARGPPARDPPARA | |
| Isophthalic Acid SCHEMBL10399350 | 0.89 | HDAC3 (0.62) | PPARAHDAC11TSHRTDP1 | |
| Octanedioate SCHEMBL29093966 | 0.89 | HDAC3 (0.62) | PPARAHDAC11TSHRTDP1 | |
| Azelaic Acid SCHEMBL10980744 | 0.89 | HDAC3 (0.62) | PPARAHDAC11TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090087400-A1 | BREATHABLE POLYURETHANES, BLENDS, AND ARTICLES | TAMARESELVY KRISHNAN | 2009-04-02 | — | — | US | claimed |
| EP-1888175-A1 | HAIR FIXING COMPOSITION BASED ON BREATHABLE POLYURETHANES | Lubrizol Advanced Materials, Inc. (US) | 2008-02-20 | — | — | EP | claimed |
| WO-2006124250-A1 | HAIR FIXING COMPOSITION BASED ON BREATHABLE POLYURETHANES | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2006-11-23 | — | — | WO | claimed |
| US-20050209428-A1 | Breathable polyurethanes, blends, and articles | LUBRIZOL ADVANCED MATERIALS, INC. | 2005-09-22 | — | — | US | claimed |
| CN-1656135-A | Breathable polyurethanes, blends, and articles | NOVEON IP HOLDINGS CORP (US) | 2005-08-17 | — | — | CN | claimed |
| JP-2005522543-A | — | — | 2005-07-28 | — | — | JP | claimed |
| US-6897281-B2 | Breathable polyurethanes, blends, and articles | NOVEON IP HOLDINGS CORP. (US) | 2005-05-24 | — | — | US | claimed |
| EP-1492831-A1 | BREATHABLE POLYURETHANES, BLENDS, AND ARTICLES | Noveon IP Holdings Corp. (US) | 2005-01-05 | — | — | EP | claimed |
| WO-2003087183-A1 | BREATHABLE POLYURETHANES, BLENDS, AND ARTICLES | NOVEON IP HOLDINGS CORP. (US) | 2003-10-23 | — | — | WO | claimed |
| US-20030195293-A1 | Breathable polyurethanes, blends, and articles | LUBRIZOL ADVANCED MATERIALS, INC. | 2003-10-16 | — | — | US | claimed |
| EP-3813991-B1 | FLAT SHEET POROUS PVC MEMBRANE | LUBRIZOL ADVANCED MAT INC (US) | 2025-11-19 | — | — | EP | disclosed |
| EP-4633783-A1 | COMPOSITIONS FOR PREPARING MEMBRANES FROM POLYMER SOLUTIONS | The Lubrizol Corporation (US) | 2025-10-22 | — | — | EP | disclosed |
| EP-4263651-B1 | ANTIFOG COMPOSITIONS AND RELATED METHODS | LUBRIZOL ADVANCED MAT INC (US) | 2024-11-20 | — | — | EP | disclosed |
| WO-2024129533-A1 | COMPOSITIONS FOR PREPARING MEMBRANES FROM POLYMER SOLUTIONS | THE LUBRIZOL CORPORATION (US) | 2024-06-20 | — | — | WO | disclosed |
| US-11952505-B1 | One component self-crosslinking coatings | SWIMC LLC (US) | 2024-04-09 | — | — | US | disclosed |
| US-20050009999-A1 | Hydroxyl-terminated thiocarbonate containing compounds, polymers, and copolymers, and polyurethanes and urethane acrylics made therefrom | LUBRIZOL ADVANCED MATERIALS, INC. | 2005-01-13 | — | — | US | disclosed |
| EP-1492831-A1 | BREATHABLE POLYURETHANES, BLENDS, AND ARTICLES | Noveon IP Holdings Corp. (US) | 2005-01-05 | — | — | EP | disclosed |
| US-20040214937-A1 | Hybrid polymer composition, and article therefrom | LUBRIZOL ADVANCED MATERIALS, INC. | 2004-10-28 | — | — | US | disclosed |
| WO-2003087183-A1 | BREATHABLE POLYURETHANES, BLENDS, AND ARTICLES | NOVEON IP HOLDINGS CORP. (US) | 2003-10-23 | — | — | WO | disclosed |
| US-20030195293-A1 | Breathable polyurethanes, blends, and articles | LUBRIZOL ADVANCED MATERIALS, INC. | 2003-10-16 | — | — | US | disclosed |