Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CHKA | P35790 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PREP | P48147 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24059733 | 1.00 | HPGD (0.59) | HPGDUSP2SMN1; SMN2EPHX1MEN1 | |
| SCHEMBL21142638 | 0.98 | HPGD (0.58) | HPGDUSP2SMN1; SMN2EPHX1MEN1 | |
| SCHEMBL21259476 | 0.98 | HPGD (0.57) | HPGDUSP2SMN1; SMN2EPHX1MEN1 | |
| SCHEMBL10253840 | 0.95 | HPGD (0.54) | HPGDUSP2SMN1; SMN2EPHX1MEN1 | |
| SCHEMBL6350119 | 0.93 | USP2 (0.55) | HPGDUSP2SMN1; SMN2EPHX1MEN1 | |
| SCHEMBL14653322 | 0.91 | USP2 (0.53) | HPGDUSP2SMN1; SMN2EPHX1MEN1 | |
| SCHEMBL14114421 | 0.89 | USP2 (0.51) | HPGDUSP2SMN1; SMN2EPHX1MEN1 | |
| SCHEMBL40106 | 0.89 | USP2 (0.51) | HPGDUSP2SMN1; SMN2EPHX1MEN1 | |
| Azetidine SCHEMBL5873670 | 0.89 | USP2 (0.55) | HPGDUSP2SMN1; SMN2EPHX1MEN1 | |
| SCHEMBL21707988 | 0.89 | HPGD (0.71) | HPGDUSP2SMN1; SMN2EPHX1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6037343-A | Fibrinogen receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-03-14 | — | — | US | disclosed |
| US-5900422-A | Fibrinogen receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1999-05-04 | — | — | US | disclosed |
| EP-0796098-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1998-04-29 | — | — | EP | disclosed |
| EP-0794779-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1998-04-29 | — | — | EP | disclosed |
| EP-0796098-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-09-24 | — | — | EP | disclosed |
| EP-0794779-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-09-17 | — | — | EP | disclosed |
| WO-1996019221-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-06-27 | — | — | WO | disclosed |
| WO-1996019223-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-06-27 | — | — | WO | disclosed |