Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 15/20 | 1.00 |
| ▸ | METAP1 | P53582 | 10/20 | 1.00 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | TPH1 | P17752 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7356692 | 1.00 | METAP2 (1.00) | METAP2METAP1MMP9TPH1 | |
| Hydrochloric Acid SCHEMBL7360347 | 0.99 | METAP2 (0.98) | METAP2METAP1MMP9TPH1 | |
| SCHEMBL12022052 | 0.87 | METAP2 (0.76) | METAP2METAP1MMP9TPH1 | |
| SCHEMBL7356697 | 0.82 | METAP2 (0.70) | METAP2METAP1 | |
| Hydrochloric Acid SCHEMBL7360631 | 0.81 | METAP2 (0.69) | METAP2METAP1 | |
| SCHEMBL7355173 | 0.81 | METAP2 (0.77) | METAP2METAP1 | |
| SCHEMBL7355989 | 0.81 | METAP2 (0.77) | METAP2METAP1 | |
| SCHEMBL7361408 | 0.81 | METAP2 (0.77) | METAP2METAP1 | |
| Hydrochloric Acid SCHEMBL7352937 | 0.80 | METAP2 (0.75) | METAP2METAP1 | |
| Hydrochloric Acid SCHEMBL7354469 | 0.80 | METAP2 (0.75) | METAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242494-B1 | ANGIOGENESIS INHIBITORS, ANTITUMOR AGENTS, DIABETIC RETINOPATHY, AND ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES | 2001-06-05 | — | — | US | claimed |
| US-6242494-B1 | ANGIOGENESIS INHIBITORS, ANTITUMOR AGENTS, DIABETIC RETINOPATHY, AND ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES | 2001-06-05 | — | — | US | disclosed |