Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 15/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | CTSE | P14091 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7278174 | 1.00 | CTSS (0.38) | CTSSCTSKAAK1RENCTSD | |
| SCHEMBL7280431 | 0.88 | CTSS (0.41) | CTSSCTSKAAK1RENCTSD | |
| SCHEMBL7290446 | 0.84 | REN (0.39) | CTSSCTSKAAK1RENCTSD | |
| SCHEMBL7326618 | 0.84 | REN (0.43) | CTSSCTSKAAK1REN | |
| SCHEMBL10592327 | 0.84 | CTSS (0.40) | CTSSCTSKAAK1RENCTSD | |
| SCHEMBL7289842 | 0.82 | CTSS (0.37) | CTSSCTSKAAK1RENCTSD | |
| SCHEMBL7278101 | 0.78 | CTSS (0.38) | CTSSCTSKAAK1RENCTSD | |
| SCHEMBL10590662 | 0.77 | CTSS (0.37) | CTSSCTSKAAK1RENCTSD | |
| SCHEMBL7280957 | 0.76 | CTSS (0.42) | CTSSCTSKAAK1RENCTSD | |
| SCHEMBL7286725 | 0.75 | REN (0.42) | CTSSCTSKAAK1RENCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0342541-A2 | Retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1989-11-23 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |