Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | CHAT | P28329 | 5/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22029544 | 1.00 | RXRA (0.49) | RXRACHATHDAC8HDAC6MTNR1A | |
| SCHEMBL10706694 | 0.80 | CHAT (0.62) | RXRACHATHDAC8HDAC6MTNR1A | |
| SCHEMBL10383610 | 0.80 | KDM4E (0.40) | HDAC8HDAC6ALDH1A1KDM4ETDP1 | |
| SCHEMBL10706700 | 0.80 | CHAT (0.62) | RXRACHATHDAC8HDAC6MTNR1A | |
| SCHEMBL10706687 | 0.80 | CHAT (0.62) | RXRACHATHDAC8HDAC6MTNR1A | |
| SCHEMBL143958 | 0.80 | RXRA (0.53) | RXRACHATHDAC8HDAC6MTNR1A | |
| SCHEMBL3721694 | 0.80 | RXRA (0.53) | RXRACHATHDAC8HDAC6MTNR1A | |
| SCHEMBL3251573 | 0.79 | RXRA (0.43) | RXRACHATHDAC8HDAC6MTNR1A | |
| SCHEMBL10437274 | 0.78 | CHAT (0.60) | RXRACHATHDAC8HDAC6MTNR1A | |
| SCHEMBL10437275 | 0.78 | CHAT (0.60) | RXRACHATHDAC8HDAC6MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901453-B1 | METHOD FOR ORGANIC REACTIONS | LABWELL AB (SE) | 2000-11-15 | — | — | EP | disclosed |
| US-6136157-A | Method for organic reactions | LABWELL AB (SE) | 2000-10-24 | — | — | US | disclosed |
| EP-0901453-A1 | METHOD FOR ORGANIC REACTIONS | Labwell AB (SE) | 1999-03-17 | — | — | EP | disclosed |
| EP-0846127-A1 | ACYLATED OLIGOPEPTIDE DERIVATIVES HAVING CELL SIGNAL INHIBITING ACTIVITY | Novartis AG (CH) | 1998-06-10 | — | — | EP | disclosed |
| WO-1997043230-A1 | METHOD FOR ORGANIC REACTIONS | LABWELL AB (SE) | 1997-11-20 | — | — | WO | disclosed |
| WO-1997008193-A1 | ACYLATED OLIGOPEPTIDE DERIVATIVES HAVING CELL SIGNAL INHIBITING ACTIVITY | NOVARTIS AG (CH) | 1997-03-06 | — | — | WO | disclosed |