Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.39 |
| ▸ | TUBB | P07437 | 4/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7358473 | 1.00 | CNR2 (0.42) | CNR2PDE4BNPC1LMNAMAPT | |
| SCHEMBL7357600 | 0.86 | PDE4A (0.42) | CNR2PDE4BNPC1LMNAMAPT | |
| SCHEMBL7357593 | 0.86 | PDE4A (0.42) | CNR2PDE4BNPC1LMNAMAPT | |
| SCHEMBL7348886 | 0.82 | TUBB4A (0.42) | PDE4BLMNAMAPTPDE4AALDH1A1 | |
| SCHEMBL7348881 | 0.82 | TUBB4A (0.42) | PDE4BLMNAMAPTPDE4AALDH1A1 | |
| SCHEMBL7349761 | 0.80 | TUBB4A (0.46) | PDE4BLMNAMAPTSMN1; SMN2PDE4A | |
| SCHEMBL7944339 | 0.80 | PDE4A (0.42) | CNR2PDE4BLMNAMAPTPDE4A | |
| Hydrochloric Acid SCHEMBL7353084 | 0.79 | PDE4A (0.41) | CNR2PDE4BLMNAMAPTPDE4A | |
| Hydrochloric Acid SCHEMBL7353088 | 0.79 | PDE4A (0.41) | CNR2PDE4BLMNAMAPTPDE4A | |
| SCHEMBL7354395 | 0.78 | PDE4A (0.45) | CNR2PDE4BMAPTPDE4AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0834508-B1 | Substituted biphenyl or phenylpyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-08-16 | — | — | EP | disclosed |
| US-5877190-A | PHOSPHODIESTERASE INHIBITOR | ADIR ET COMPAGNIE (FR) | 1999-03-02 | — | — | US | disclosed |
| EP-0834508-A1 | Substituted biphenyl or phenylpyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-04-08 | — | — | EP | disclosed |