Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PELI1 | Q96FA3 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 4/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7353084 | 0.99 | PDE4A (0.41) | PDE4APDE4BPELI1GAAAKR1C3 | |
| Hydrochloric Acid SCHEMBL7353088 | 0.99 | PDE4A (0.41) | PDE4APDE4BPELI1GAAAKR1C3 | |
| SCHEMBL7357593 | 0.91 | PDE4A (0.42) | PDE4APDE4BPELI1GAAAKR1C3 | |
| SCHEMBL7357600 | 0.91 | PDE4A (0.42) | PDE4APDE4BPELI1GAAAKR1C3 | |
| SCHEMBL7354395 | 0.89 | PDE4A (0.45) | PDE4APDE4BPELI1GAAAKR1C3 | |
| SCHEMBL7349221 | 0.81 | F7 (0.46) | PDE4APDE4BPELI1MAPTALDH1A1 | |
| SCHEMBL7349224 | 0.81 | F7 (0.46) | PDE4APDE4BPELI1MAPTALDH1A1 | |
| SCHEMBL7357532 | 0.80 | ALDH1A1 (0.46) | PDE4APDE4BPELI1GAAAKR1C3 | |
| SCHEMBL7357536 | 0.80 | ALDH1A1 (0.46) | PDE4APDE4BPELI1GAAAKR1C3 | |
| SCHEMBL7358477 | 0.80 | CNR2 (0.42) | PDE4APDE4BPELI1GAAAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0834508-B1 | Substituted biphenyl or phenylpyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-08-16 | — | — | EP | disclosed |
| EP-0834508-A1 | Substituted biphenyl or phenylpyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-04-08 | — | — | EP | disclosed |