Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | CLK3 | P49761 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | ITK | Q08881 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5748255 | 0.80 | MET (0.43) | ALDH1A1METMAPTMEN1POLB | |
| SCHEMBL14387620 | 0.78 | NTRK1 (0.40) | KDM4EALDH1A1HPGDNTRK1DYRK1A | |
| SCHEMBL28369687 | 0.76 | CHEK1 (0.55) | KDM4EALDH1A1HPGDDYRK1ACDK5 | |
| SCHEMBL5484683 | 0.75 | KDM4E (0.53) | KDM4EALDH1A1HPGDDYRK1AITK | |
| SCHEMBL20674039 | 0.75 | KDM4E (0.53) | KDM4EALDH1A1HPGDDYRK1AITK | |
| SCHEMBL7357858 | 0.75 | KDM4E (0.53) | KDM4EALDH1A1HPGDDYRK1AITK | |
| SCHEMBL30548013 | 0.75 | KDM4E (0.53) | KDM4EALDH1A1HPGDDYRK1AITK | |
| SCHEMBL30039348 | 0.75 | KDM4E (0.53) | KDM4EALDH1A1HPGDDYRK1AITK | |
| SCHEMBL24056601 | 0.74 | MET (0.40) | KDM4EALDH1A1HPGDMETPOLB | |
| SCHEMBL30024695 | 0.74 | MET (0.40) | KDM4EALDH1A1HPGDMETPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991001316-A1 | NEW 9-AZABICYCLO[3.3.1]NONANE-DERIVATE | BEECHAM GROUP PLC (GB) | 1991-02-07 | — | — | WO | disclosed |