Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 11/20 | 0.65 |
| ▸ | CTSK | P43235 | 10/20 | 0.65 |
| ▸ | CTSB | P07858 | 4/20 | 0.65 |
| ▸ | CTSL | P07711 | 2/20 | 0.65 |
| ▸ | AKT1 | P31749 | 1/20 | 0.54 |
| ▸ | ACE | P12821 | 1/20 | 0.54 |
| ▸ | REN | P00797 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7295862 | 0.92 | CTSS (0.69) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL5050550 | 0.92 | CTSS (0.69) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL7295855 | 0.92 | CTSS (0.69) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL3498556 | 0.88 | CTSS (0.64) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL7287865 | 0.86 | CTSK (0.61) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL7287859 | 0.86 | CTSK (0.61) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL5709614 | 0.85 | CTSS (0.65) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL29964830 | 0.85 | CTSS (0.65) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL7268466 | 0.84 | CTSS (0.56) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL7296225 | 0.84 | CTSS (0.56) | CTSSCTSKCTSBCTSLAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684830-A4 | INHIBITORS OF THROMBOSIS. | CORVAS INT INC (US) | 1996-04-17 | — | — | EP | disclosed |
| EP-0684830-A1 | INHIBITORS OF THROMBOSIS | CORVAS INTERNATIONAL, INC. (US) | 1995-12-06 | — | — | EP | disclosed |
| WO-1994017817-A1 | INHIBITORS OF THROMBOSIS | CORVAS INTERNATIONAL, INC. (US) | 1994-08-18 | — | — | WO | disclosed |