Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.52 |
| ▸ | PPARG | P37231 | 3/20 | 0.52 |
| ▸ | FBP1 | P09467 | 8/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL655568 | 0.90 | PPARA (0.61) | PPARAPPARGFBP1CYP3A4ABCB11 | |
| SCHEMBL7331938 | 0.87 | CYP3A4 (0.53) | CYP3A4TSHRLMNAL3MBTL1TP53 | |
| SCHEMBL655339 | 0.81 | CYP3A4 (0.51) | PPARAPPARGFBP1CYP3A4ABCB11 | |
| SCHEMBL197882 | 0.76 | PPARA (0.64) | PPARAPPARGFBP1CYP3A4ABCB11 | |
| SCHEMBL20730087 | 0.76 | PPARA (0.64) | PPARAPPARGFBP1CYP3A4ABCB11 | |
| SCHEMBL12670824 | 0.75 | PPARA (0.62) | PPARAPPARGFBP1CYP3A4ABCB11 | |
| SCHEMBL10459364 | 0.75 | CYP3A4 (0.45) | PPARAPPARGFBP1CYP3A4ABCB11 | |
| SCHEMBL6178916 | 0.75 | MAOB (0.52) | PPARAPPARGFBP1ALDH1A1 | |
| SCHEMBL1454525 | 0.75 | L3MBTL1 (0.57) | CYP3A4TSHRLMNAL3MBTL1KMT2A | |
| Hydrochloric Acid SCHEMBL6983185 | 0.75 | CYP3A4 (0.47) | PPARAPPARGFBP1CYP3A4ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |
| EP-0687253-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | Roche Diagnostics GmbH (DE) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020467-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1994-09-15 | — | — | WO | disclosed |