Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.52 |
| ▸ | PPARA | Q07869 | 5/20 | 0.50 |
| ▸ | PPARG | P37231 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL655568 | 0.83 | PPARA (0.61) | PPARAPPARGALDH1A1FBP1 | |
| SCHEMBL2668319 | 0.78 | PPARA (0.54) | MAOBPPARAPPARGALDH1A1PPARD | |
| SCHEMBL6081371 | 0.78 | PPARA (0.61) | PPARAPPARGALDH1A1FBP1 | |
| SCHEMBL14943944 | 0.77 | CYP3A4 (0.44) | MAOBPPARAPPARGALDH1A1FBP1 | |
| SCHEMBL6180358 | 0.77 | MGLL (0.50) | PPARAPPARGPPARD | |
| SCHEMBL11431131 | 0.77 | PPARA (0.62) | MAOBPPARAPPARGALDH1A1 | |
| SCHEMBL2822423 | 0.77 | NR4A2 (0.56) | MAOBPPARAPPARGALDH1A1NR4A2 | |
| SCHEMBL13039762 | 0.76 | THRA (0.43) | MAOBALDH1A1 | |
| SCHEMBL15271467 | 0.75 | CYP3A4 (0.48) | MAOBPPARAPPARGALDH1A1 | |
| SCHEMBL7358718 | 0.75 | PPARA (0.52) | PPARAPPARGALDH1A1FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945445-B9 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2005-12-28 | — | — | EP | disclosed |
| EP-0945445-B1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6239131-B1 | WHICH HAVE GASTRIN AND/OR CCK-B (CHOLECYSTOKININ-B) RECEPTOR ANTAGONISM, USEFUL AS REMEDIES FOR GASTRIC ULCER AND GASTROINTESTINAL MOVEMENT DISORDER. | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-29 | — | — | US | disclosed |
| EP-0945445-A1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |