Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | FDPS | P14324 | 5/20 | 0.45 |
| ▸ | EBP | Q15125 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7356108 | 0.93 | MEN1 (0.47) | MEN1FDPSEBPSIGMAR1LTA4H | |
| SCHEMBL7356652 | 0.85 | MAOB (0.45) | MEN1SMN1; SMN2 | |
| SCHEMBL7352809 | 0.82 | SIGMAR1 (0.60) | FDPSEBPSIGMAR1CHRM2CHRM4 | |
| SCHEMBL7359198 | 0.82 | FDPS (0.41) | MEN1FDPSSIGMAR1LTA4HKDM4E | |
| SCHEMBL7355511 | 0.81 | SIGMAR1 (0.50) | MEN1EBPSIGMAR1KCNH2LMNA | |
| SCHEMBL7361735 | 0.78 | SIGMAR1 (0.50) | MEN1EBPSIGMAR1KCNH2LMNA | |
| SCHEMBL7355112 | 0.78 | SIGMAR1 (0.44) | MEN1EBPSIGMAR1KDM4EALDH1A1 | |
| SCHEMBL7353845 | 0.78 | SIGMAR1 (0.52) | MEN1EBPSIGMAR1KCNH2LMNA | |
| SCHEMBL7359798 | 0.78 | SIGMAR1 (0.52) | MEN1FDPSEBPSIGMAR1KCNH2 | |
| SCHEMBL7357622 | 0.76 | SIGMAR1 (0.53) | MEN1FDPSEBPSIGMAR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699182-A1 | CYCLOPROPYLACETONITRILE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF AS DRUGS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1996-03-06 | — | — | EP | claimed |
| WO-1995025087-A1 | CYCLOPROPYLACETONITRILE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF AS DRUGS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1995-09-21 | — | — | WO | claimed |