Nicotredole

Nicotredole

SCHEMBL735897

O=C(NCCc1c[nH]c2ccccc12)c1cccnc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 1.00
KMT2A Q03164 5/20 1.00
CDK4 P11802 5/20 0.80
CCND1 P24385 5/20 0.80
NPC1 O15118 3/20 0.75
RAB9A P51151 3/20 0.75
GAA P10253 1/20 0.74
HPGD P15428 1/20 0.74
ALDH1A1 P00352 1/20 0.71
GLA P06280 1/20 0.71
SMN1; SMN2 Q16637 1/20 0.70
PTGS2 P35354 1/20 0.69
SIRT1 Q96EB6 5/20 0.65
TRPV1 Q8NER1 1/20 0.63
POLB P06746 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nicotredole SCHEMBL29454469 1.00 MEN1 (1.00) MEN1KMT2ACDK4CCND1NPC1
Nicotredole SCHEMBL17824507 0.90 MEN1 (0.81) MEN1KMT2ACDK4CCND1NPC1
SCHEMBL13942359 0.88 CDK4 (0.83) MEN1KMT2ACDK4CCND1NPC1
SCHEMBL7960829 0.87 MEN1 (0.78) MEN1KMT2ACDK4CCND1NPC1
Behenic Acid SCHEMBL4075758 0.87 MEN1 (0.76) MEN1KMT2ACDK4CCND1NPC1
SCHEMBL25253674 0.86 HPGD (0.79) MEN1KMT2ACDK4CCND1NPC1
SCHEMBL4331421 0.86 MEN1 (1.00) MEN1KMT2ACDK4CCND1NPC1
SCHEMBL23470288 0.86 MEN1 (0.75) MEN1KMT2ACDK4CCND1NPC1
Nicotredole SCHEMBL2544181 0.85 MEN1 (0.72) MEN1KMT2ACDK4CCND1NPC1
Cyanide SCHEMBL31484737 0.83 MEN1 (0.92) MEN1KMT2ACDK4CCND1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025132327-A1 USE OF QUORUM QUENCHING (QQ) COMPOUNDS FOR AVOIDING THE FORMATION OF BIOFILMS, BIOFOULING OR BIOCORROSION ON SURFACES Johannes Gutenberg-Universität Mainz (DE) 2025-06-26 WO claimed
CN-117137048-A Flavor composition, food comprising the same, and method for increasing the flavor intensity of the umami taste of food 马斯公司 2023-12-01 CN claimed
CN-114181944-A Mutant gene and use thereof 中国科学院动物研究所 2022-03-15 CN claimed
EP-3207029-B1 TRYPTAMIDE COMPOSITIONS AND METHODS OF USE SIGNUM BIOSCIENCES INC (US) 2021-08-04 EP claimed
CN-107108495-B Chromate compositions and methods of use 希格诺生物科学有限公司 2021-07-16 CN claimed
CN-105198786-A Aryl-substituted amide compound, preparing method thereof, medicine composition comprising same, and application thereof INST MED BIOTECHNOLOGY CAMS 2015-12-30 CN claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
US-7417027-B2 Linear and cyclic melanocortin receptor-specific peptides PALATIN TECHNOLOGIES, INC. (US) 2008-08-26 US claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
EP-1441750-A4 LINEAR AND CYCLIC MELANOCORTIN RECEPTOR-SPECIFIC PEPTIDES PALATIN TECHNOLOGIES INC (US) 2006-10-18 EP claimed
US-20050038230-A1 Linear and cyclic melanocortin receptor-specific peptides PALATIN TECHNOLOGIES, INC. (US) 2005-02-17 US claimed
EP-1441750-A2 LINEAR AND CYCLIC MELANOCORTIN RECEPTOR-SPECIFIC PEPTIDES Palatin Technologies, Inc. (US) 2004-08-04 EP claimed
WO-2003006620-A2 LINEAR AND CYCLIC MELANOCORTIN RECEPTOR-SPECIFIC PEPTIDES PALATIN TECHNOLOGIES, INC. (US) 2003-01-23 WO claimed
EP-0770091-B1 COMPOUNDS FOR REVERSING DRUG RESISTANCE SARKADI BALAZS (HU) 2000-03-01 EP claimed
EP-0770091-A1 COMPOUNDS FOR REVERSING DRUG RESISTANCE Sarkadi, Balazs (HU) 1997-05-02 EP claimed
WO-1995031474-A1 COMPOUNDS FOR REVERSING DRUG RESISTANCE SARKADI BALAZS (HU) 1995-11-23 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050038230-A1 Linear and cyclic melanocortin receptor-specific peptides MC1R, MC3R, MC5R MEN1 582/4885KMT2A 1546/4885CDK4 3153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.