Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.78 |
| ▸ | CDK4 | P11802 | 2/20 | 0.63 |
| ▸ | CCND1 | P24385 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nicotredole SCHEMBL29454469 | 0.87 | MEN1 (1.00) | MEN1KMT2ACDK4CCND1GAA | |
| Nicotredole SCHEMBL735897 | 0.87 | MEN1 (1.00) | MEN1KMT2ACDK4CCND1GAA | |
| SCHEMBL7976825 | 0.83 | SMN1; SMN2 (0.71) | MEN1KMT2AGAAHPGDALDH1A1 | |
| SCHEMBL7972279 | 0.79 | SMN1; SMN2 (0.66) | MEN1KMT2AGAAHPGDALDH1A1 | |
| SCHEMBL28167913 | 0.78 | ALDH1A1 (0.64) | MEN1KMT2ARAB9AALDH1A1GLA | |
| Nicotredole SCHEMBL17824507 | 0.78 | MEN1 (0.81) | MEN1KMT2ACDK4CCND1GAA | |
| SCHEMBL10069200 | 0.77 | AANAT (0.77) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL1849735 | 0.77 | LMNA (0.65) | MEN1KMT2AGAAHPGDRAB9A | |
| Behenic Acid SCHEMBL4075758 | 0.76 | MEN1 (0.76) | MEN1KMT2ACDK4CCND1GAA | |
| SCHEMBL13942359 | 0.76 | CDK4 (0.83) | MEN1KMT2ACDK4CCND1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055109-A1 | AROMATIC AMIDES ACTING ON MELANOCORTIN RECEPTORS | MELACURE THERAPEUTICS AB (SE) | 2001-08-02 | — | — | WO | claimed |
| WO-2001055109-A1 | AROMATIC AMIDES ACTING ON MELANOCORTIN RECEPTORS | MELACURE THERAPEUTICS AB (SE) | 2001-08-02 | — | — | WO | disclosed |