Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.61 |
| ▸ | BRD2 | P25440 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Azepane SCHEMBL21049976 | 0.94 | BRD4 (0.71) | BRD4BRD2KDM4EGAAPOLB | |
| Methylpyrrolidone SCHEMBL2781641 | 0.94 | BRD4 (0.71) | BRD4BRD2KDM4EGAAPOLB | |
| SCHEMBL14747422 | 0.87 | BRD4 (0.80) | BRD4BRD2GAAACHEALDH1A1 | |
| SCHEMBL329328 | 0.87 | BRD4 (0.80) | BRD4BRD2GAAACHEALDH1A1 | |
| SCHEMBL26047696 | 0.87 | BRD4 (0.80) | BRD4BRD2GAAACHEALDH1A1 | |
| SCHEMBL6886758 | 0.87 | BRD4 (0.80) | BRD4BRD2GAAACHEALDH1A1 | |
| SCHEMBL1626056 | 0.87 | BRD4 (0.80) | BRD4BRD2GAAACHEALDH1A1 | |
| SCHEMBL54926 | 0.87 | — | — | |
| SCHEMBL6885804 | 0.87 | BRD4 (0.80) | BRD4BRD2GAAACHEALDH1A1 | |
| SCHEMBL26047693 | 0.87 | BRD4 (0.80) | BRD4BRD2GAAACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527761-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | Beecham Group p.l.c. (GB) | 1993-02-24 | — | — | EP | disclosed |
| WO-1991015506-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | BEECHAM GROUP PLC (GB) | 1991-10-17 | — | — | WO | disclosed |