Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15331888 | 0.86 | KMT2A (0.49) | RAB9AMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9152090 | 0.84 | PTGDR2 (0.51) | RAB9AMAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL29953474 | 0.84 | ALDH1A1 (0.53) | RAB9AMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2556381 | 0.82 | SMN1; SMN2 (0.50) | RAB9AMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7367561 | 0.82 | ALDH1A1 (0.55) | RAB9AMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2561464 | 0.81 | ALDH1A1 (0.51) | RAB9AMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2556198 | 0.81 | ALDH1A1 (0.46) | RAB9AMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL29956598 | 0.81 | MAPT (0.46) | RAB9AMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2552640 | 0.79 | MAPT (0.48) | RAB9AMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2563279 | 0.78 | SMN1; SMN2 (0.58) | RAB9AMAPTALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378718-A | Cardiovascular activity, hypotensive | CEDONA PHARMACEUTICALS B.V. (NL) | 1995-01-03 | — | — | US | disclosed |
| EP-0541634-A1 | 1,4-DIHYDROPYRIDINE DERIVATIVES | CEDONA PHARMACEUTICALS B.V. (NL) | 1993-05-19 | — | — | EP | disclosed |
| WO-1992002503-A1 | NOVEL 1,4-DIHYDROPYRIDINE DERIVATIVES | CEDONA PHARMACEUTICALS BV (NL) | 1992-02-20 | — | — | WO | disclosed |