Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 9/20 | 0.48 |
| ▸ | TMPRSS6 | Q8IU80 | 4/20 | 0.48 |
| ▸ | KLK1 | P06870 | 2/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | C1S | P09871 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359286 | 0.84 | PARP1 (0.61) | PARP1CA12CA1CA2CA6 | |
| Benzamidine SCHEMBL5241617 | 0.82 | F2 (0.67) | PARP1F2TMPRSS6KLK1KLK5 | |
| Benzamidine SCHEMBL5238261 | 0.82 | F2 (0.67) | PARP1F2TMPRSS6KLK1KLK5 | |
| Trifluoroacetic Acid SCHEMBL38651965 | 0.82 | PARP1 (0.56) | PARP1F2TMPRSS6KLK1KLK5 | |
| Hydrochloric Acid SCHEMBL3909792 | 0.82 | PRSS1 (0.63) | PARP1F2KLK1PRSS1PRSS2 | |
| Resorcinol SCHEMBL11567030 | 0.80 | ALDH1A1 (0.57) | PARP1CA12CA1CA2CA6 | |
| Trifluoroacetic Acid SCHEMBL13269627 | 0.75 | KLK1 (0.47) | F2TMPRSS6KLK1KLK5PRSS1 | |
| Trifluoroacetic Acid SCHEMBL10277408 | 0.74 | PARP1 (0.59) | PARP1 | |
| SCHEMBL6263144 | 0.74 | ACHE (0.59) | PARP1CA12CA1CA2CA6 | |
| Trifluoroacetic Acid SCHEMBL29713373 | 0.74 | PARP1 (0.59) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8227506-B2 | Benzamidine compound | AJINOMOTO., INC. (JP) | 2012-07-24 | — | — | US | disclosed |
| US-20100105731-A2 | NOVEL BENZAMIDINE COMPOUND | AJINOMOTO CO., INC. (JP) | 2010-04-29 | — | — | US | disclosed |
| US-20080021065-A1 | NOVEL BENZAMIDINE COMPOUND | AJINOMOTO CO. INC (JP) | 2008-01-24 | — | — | US | disclosed |
| EP-1847527-A1 | NOVEL BENZAMIDINE COMPOUND | Ajinomoto Co., Inc. (JP) | 2007-10-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105731-A2 | NOVEL BENZAMIDINE COMPOUND | SERPINC1, F11, TFPI | PARP1 4095/4885CA12 2851/4885CA1 2306/4885 |
| US-20080021065-A1 | NOVEL BENZAMIDINE COMPOUND | SERPINC1, F11, TFPI | PARP1 4095/4885CA12 2851/4885CA1 2306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.