Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6ST | P40189 | 4/20 | 0.55 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | IDH1 | O75874 | 3/20 | 0.44 |
| ▸ | GRM5 | P41594 | 5/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359514 | 1.00 | IL6ST (0.55) | IL6STNAAAIDH1GRM5FAAH | |
| SCHEMBL30984014 | 0.88 | NAAA (0.51) | IL6STNAAAIDH1FAAHSTAT3 | |
| SCHEMBL7653046 | 0.87 | IL6ST (0.44) | IL6STIDH1GRM5FAAH | |
| SCHEMBL6598726 | 0.87 | NAAA (0.53) | IL6STNAAAIDH1FAAHSTAT3 | |
| SCHEMBL2072708 | 0.87 | NAAA (0.53) | IL6STNAAAIDH1FAAHSTAT3 | |
| SCHEMBL9970272 | 0.85 | IL6ST (0.66) | IL6STNAAAIDH1FAAHSTAT3 | |
| SCHEMBL14523671 | 0.85 | IL6ST (0.66) | IL6STNAAAIDH1FAAHSTAT3 | |
| SCHEMBL1257034 | 0.84 | IL6ST (0.51) | IL6STNAAAIDH1FAAH | |
| SCHEMBL30984038 | 0.83 | IL6ST (0.56) | IL6STNAAAIDH1FAAHSTAT3 | |
| SCHEMBL475582 | 0.82 | NAAA (0.58) | IL6STNAAAIDH1FAAHSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0342541-A2 | Retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1989-11-23 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |