Sugi Predict

Sugi Predict / Compounds / SCHEMBL30984038

SCHEMBL30984038

SCHEMBL30984038

CC(C)[C@@H]1COC(=O)N1C(=O)[C@H](C)CCOCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ IL6ST P40189 5/20 0.56
▸ STAT3 P40763 1/20 0.41
▸ IDH1 O75874 7/20 0.41
▸ NAAA Q02083 1/20 0.39
▸ AGTR2 P50052 1/20 0.38
▸ FAAH O00519 2/20 0.37
▸ CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6601336 0.94 IL6ST (0.54) IL6STSTAT3IDH1NAAAAGTR2
SCHEMBL2070699 0.94 IL6ST (0.54) IL6STSTAT3IDH1NAAAAGTR2
SCHEMBL20695126 0.86 PPARA (0.47) IL6STIDH1NAAAAGTR2FAAH
SCHEMBL19423219 0.86 PPARA (0.47) IL6STIDH1NAAAAGTR2FAAH
SCHEMBL20695124 0.86 PPARA (0.47) IL6STIDH1NAAAAGTR2FAAH
SCHEMBL19423252 0.86 PPARA (0.47) IL6STIDH1NAAAAGTR2FAAH
SCHEMBL20695123 0.86 PPARA (0.47) IL6STIDH1NAAAAGTR2FAAH
SCHEMBL8826143 0.83 IL6ST (0.59) IL6STSTAT3IDH1NAAAFAAH
SCHEMBL7359508 0.83 IL6ST (0.55) IL6STSTAT3IDH1NAAAFAAH
SCHEMBL7359514 0.83 IL6ST (0.55) IL6STSTAT3IDH1NAAAFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630410-A1 POLQ INHIBITORS Astrazeneca AB (SE) 2025-10-15 — — EP disclosed
WO-2024121753-A1 POLQ INHIBITORS ASTRAZENECA AB (SE) 2024-06-13 — — WO disclosed