Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360298 | 0.82 | TAAR1 (0.33) | L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL6296227 | 0.76 | GAA (0.39) | GAAL3MBTL1ALDH1A1BACE1TSHR | |
| SCHEMBL6297922 | 0.76 | GAA (0.39) | GAAL3MBTL1ALDH1A1BACE1TSHR | |
| SCHEMBL6608641 | 0.75 | ASAH1 (0.37) | GAAL3MBTL1ALDH1A1TSHRLMNA | |
| SCHEMBL8008899 | 0.67 | FFAR1 (0.43) | LMNA | |
| SCHEMBL7078065 | 0.66 | WRN (0.36) | GAAL3MBTL1ALDH1A1BACE1TSHR | |
| SCHEMBL6296615 | 0.65 | TAAR1 (0.38) | ALDH1A1LMNAKDM4E | |
| SCHEMBL6296613 | 0.65 | TAAR1 (0.38) | ALDH1A1LMNAKDM4E | |
| SCHEMBL6296215 | 0.63 | KDM4E (0.37) | GAAALDH1A1LMNAKDM4E | |
| SCHEMBL22015030 | 0.63 | GAA (0.48) | GAAL3MBTL1ALDH1A1BACE1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112269-A2 | HIV PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-07-04 | — | — | EP | claimed |
| WO-2000015634-A2 | HIV PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2000-03-23 | — | — | WO | claimed |
| EP-1112269-A2 | HIV PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000015634-A2 | HIV PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2000-03-23 | — | — | WO | disclosed |